Diphenhydramine

Diphenhydramine is a drowsy antihistamine that can be used to treat temporary insomnia as well as coughs and colds.  Read More See less

It works by blocking the effect of histamine, a chemical in your brain that is released during an allergic reaction. This can reduce symptoms of cold and flu, as well as making you feel sleepy. 

Sort
  1. Benylin Children's Night Coughs - 125ml - (6 Years +)

    Sugar Free

    This item is eligible for express delivery. If all of the items in your basket are eligible you will be shown the express delivery shipping option.

    £4.99
  2. Save 9%

    Benylin 4 Flu – 24 Tablets

    (1)
    This is a pharmacy medicine which means you will have to answer a short questionnaire before adding to your basket.

    This item is eligible for express delivery. If all of the items in your basket are eligible you will be shown the express delivery shipping option.

    Now
    £6.69
    RRP £7.39
  3. Covonia Night Time Formula – 150ml

    (6)
    This is a pharmacy medicine which means you will have to answer a short questionnaire before adding to your basket.

    This item is eligible for express delivery. If all of the items in your basket are eligible you will be shown the express delivery shipping option.

    £5.99
  4. Benylin Day & Night Cold & Flu Relief – 16 Tablets

    (3)
    This is a pharmacy medicine which means you will have to answer a short questionnaire before adding to your basket.

    This item is eligible for express delivery. If all of the items in your basket are eligible you will be shown the express delivery shipping option.

    £5.79
  5. Benylin Chesty Coughs Original - 300ml

    (20)
    This is a pharmacy medicine which means you will have to answer a short questionnaire before adding to your basket.

    This item is eligible for express delivery. If all of the items in your basket are eligible you will be shown the express delivery shipping option.

    £10.79
  6. Nytol Original 25mg - 20 Tablets

    (6)
    This item is eligible for express delivery. If all of the items in your basket are eligible you will be shown the express delivery shipping option.

    £5.69
  7. Nytol One-A-Night 50mg - 20 Tablets

    (33)
    This is a pharmacy medicine which means you will have to answer a short questionnaire before adding to your basket.

    This item is eligible for express delivery. If all of the items in your basket are eligible you will be shown the express delivery shipping option.

    £8.09
  8. Benylin Dry Cough Night Syrup – 150ml

    (15)
    This is a pharmacy medicine which means you will have to answer a short questionnaire before adding to your basket.

    This item is eligible for express delivery. If all of the items in your basket are eligible you will be shown the express delivery shipping option.

    £6.99
  9. Numark Chesty Cough Expectorant – 200ml

    (6)
    This is a pharmacy medicine which means you will have to answer a short questionnaire before adding to your basket.

    £3.99
  10. Numark Night Time Sleep Aid 25mg - 20 Tablets

    (16)
    This item is eligible for express delivery. If all of the items in your basket are eligible you will be shown the express delivery shipping option.

    £3.29
  11. Benylin Mucus Cough Relief Night Syrup – 150ml

    (7)
    This is a pharmacy medicine which means you will have to answer a short questionnaire before adding to your basket.

    This item is eligible for express delivery. If all of the items in your basket are eligible you will be shown the express delivery shipping option.

    £9.99
  12. Benylin Chesty Coughs Original - 150ml

    (8)
    This is a pharmacy medicine which means you will have to answer a short questionnaire before adding to your basket.

    This item is eligible for express delivery. If all of the items in your basket are eligible you will be shown the express delivery shipping option.

    £7.29
  13. Panadol Night Pain - 20 Tablets

    (23)
    This is a pharmacy medicine which means you will have to answer a short questionnaire before adding to your basket.

    This item is eligible for express delivery. If all of the items in your basket are eligible you will be shown the express delivery shipping option.

    £5.79
  14. Nytol Liquid Caramel Flavour 10mg/5ml - 300ml

    (26)
    This item is eligible for express delivery. If all of the items in your basket are eligible you will be shown the express delivery shipping option.

    £10.99
  15. Save 9%
    Out of Stock
  16. Out of Stock

    Antihistamine Cream - 25g (Brand may Vary)

    (14)
    The brand we send out can change from time to time, but the active ingredient(s) will be identical and always of the same quality.

    £3.49
  17. Out of Stock

    Lunox Max Sleep Aid 50mg 20 Tablets

    This is a pharmacy medicine which means you will have to answer a short questionnaire before adding to your basket.

    £7.99
  18. Out of Stock

    Lunox Sleep Aid Tablets 25mg 20 Tablets

    This is a pharmacy medicine which means you will have to answer a short questionnaire before adding to your basket.

    £5.89

19 Items

per page
Why shop with Chemist4U?

Free delivery when you spend over £30

100% discreet delivery for every item ordered

Fully regulated UK pharmacy

Frequently Asked Questions

Is diphenhydramine an antihistamine?

Yes, diphenhydramine is a type of drowsy antihistamine, but it’s not just used to treat allergies such as hay fever. It’s also used for short-term sleep problems, cough and cold symptoms, in addition to eczema, hives and insect bites and stings.


Does diphenhydramine have side effects?

Like all medicines, diphenhydramine may cause side effects in some people, but these won’t affect everybody. Side effects may include:


  • Drowsiness

  • Dry mouth

  • Dizziness

  • Trouble concentrating

Can I drink alcohol if I'm taking diphenhydramine?

It’s important that you don’t drink alcohol while you’re taking diphenhydramine. This is because the combination of alcohol and diphenhydramine can make you sleep very deeply. This may cause you not to be able to breathe properly and you may have difficulty waking up.

What is the usual diphenhydramine dosage for sleep?

If you’re taking diphenhydramine for short-term insomnia, your tablets will either be 25mg or 50mg in strength. You should take a tablet 20 minutes before you go to bed.

© 2024 Chemist4U. Innox Trading Ltd, 35-37 Greenhey Place, Skelmersdale, Lancashire, WN8 9SA, GB. All rights reserved. Registered and regulated UK pharmacy with the GPhC (registered premises 9011784). Registered in England No. 07262043 | VAT Registration No. GB140138454