Nytol Liquid Caramel Flavour 10mg/5ml - 300ml

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  • The maximum purchase for this product is 2
Shamir Patel - Superintendent Pharmacist & Director
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Shamir Patel


Superintendent Pharmacist & Director



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What is Nytol Liquid Caramel Flavour Solution?

Nytol Liquid Caramel Flavour Solution is a remedy for mild allergies and hay fever that can be used by children of all ages. It’s also suitable for adults and children over the age of 16 who are struggling with insomnia and need help to get a good night’s sleep. Every 5ml of Nytol liquid contains 10mg of an active ingredient called diphenhydramine, an antihistamine that can relieve allergic reactions and make you drowsy, so it’s easier to drift off to sleep at night.


How does diphenhydramine help to relieve hay fever or allergic reactions?

Diphenhydramine hydrochloride (HCL) works as an antihistamine, which means it blocks a natural substance called histamine. Histamine is created by your body when you come into contact with something you’re allergic to, and it triggers parts of your body to produce allergy symptoms so it can try to remove the allergen from your body. This is why you experience coughing, sneezing, a runny nose, itchy eyes, and all kinds of other symptoms when you have hay fever or another allergy. Diphenhydramine blocks histamine, which prevents your body from producing these symptoms and making your hay fever or allergies much more manageable.


Is Nytol Liquid suitable for children?

Nytol Liquid can be used to relieve mild allergies, hay fever, and mild reactions to bites and stings in children of all ages. However, if your child is younger than 5 you should speak to your doctor or pharmacist before giving them this medication. This medicine is NOT suitable to be used as a remedy for sleep disturbances or insomnia in children younger than 16. If your child is suffering from sleeplessness, you should ask a medical professional for advice so they can help you to choose a suitable treatment.


How does diphenhydramine HCL help to relieve sleeplessness in adults?

Diphenhydramine HCL helps to ease sleeplessness in adults because it’s an antihistamine. As well as triggering allergy symptoms, histamine is involved with your brain’s waking system. This means that by blocking histamine, this product can make you feel sleepy or drowsy, helping you to fall asleep more easily and easing insomnia.


What is insomnia?

Insomnia means that you regularly have trouble falling asleep or often wake up in the night. Most people suffer from the occasional sleepless night, but if you have insomnia then you will regularly feel tired or irritable throughout the day, lie awake for long periods at night, and could even struggle to have a nap during the day despite feeling exhausted. Some of the most common causes of insomnia include:

  • Jet lag
  • Anxiety, depression, stress
  • Worrying about an upcoming event, such as an exam or driving test
  • Drinking alcohol, caffeine, nicotine
  • Taking recreational drugs
  • A noisy environment
  • Your bedroom is too hot or too cold
  • An uncomfortable bed
  • Shift work disrupting your sleep pattern


Can I take this medicine if I’m pregnant or breastfeeding?

If you’re pregnant or breastfeeding you should not take diphenhydramine. If you’re pregnant or breastfeeding and are suffering from insomnia or mild allergies, you should speak to your doctor or pharmacist so they can help you to choose an alternative treatment or suggest some lifestyle changes that could help.


Can I drive after taking this product?

This medicine can make you feel drowsy or sleepy, or give you blurred vision. This may affect your attention or reaction times. You should not attempt to drive or use tools or machinery unless you are sure that this medication hasn’t affected you in this way.


Can I drink alcohol while I’m taking Nytol Liquid?

You should avoid drinking alcohol while you’re taking Nytol Liquid. Drinking alcohol while using this product could make side effects like drowsiness more extreme.


Can I take this medicine if I’m taking any other medications?

If you’re taking other medications, then you should speak to your doctor or pharmacist before taking Nytol Liquid. When you take two medications together, they may interact causing unwanted side effects or making your medication less effective. Be especially sure to speak to your doctor or pharmacist if you are taking:

  • Any other antihistamines, including those included in cough and cold medications, and treatments used on your skin
  • Sedatives which are used to treat anxiety, e.g. diazepam
  • Hypnotics used to help you to sleep better, e.g. nitrazepam
  • Depression medications known as MAOIs (monoamine oxidase inhibitors), e.g. phenelzine. Speak to your doctor or pharmacist before taking this product if you have stopped taking an MAOI within the past 2 weeks
  • Metoprolol, which is a medication used to treat high blood pressure, angina, irregular heartbeat, or overactive thyroid. Metoprolol is also known as a beta-blocker
  • Venlafaxine, which is used to treat depression
  • Anticholinergics, which are used in Parkinson’s disease, irritable bowel syndrome (IBS), and incontinence, e.g. procyclidine, trihexyphenidyl, atropine, oxybutine, fesoterodine
  • Tricyclic antidepressants, e.g. imipramine, amitriptyline


How to take Nytol Liquid Caramel Flavour

The recommended dose of Nytol Liquid Caramel Flavour will depend on what you’re using it as a sleep aid or to treat hay fever and allergies.


For sleep

If you’re an adult and want to use this product as a sleep aid, you should take 10 – 25ml of this medicine at bedtime or if you struggle to fall asleep. Do not take more than one dose a night, and do not use as a sleep aid in children younger than 16.


For hay fever, other minor allergies, insect bites and stings

  • Adults and children over the age of 12 years: Two 5ml spoonfuls 3 – 4 times a day
  • Children aged 6 – 12 years: One 5ml spoonful 3 times a day
  • Children aged 1 – 6 years: Half to one 5ml spoonful 3 times a day
  • Children younger than 1-year-old: Half a 5ml spoonful 3 times a day

Do not take more than the recommended dose at any time. If you’re ever unsure about how much of this product to use, ask your doctor or pharmacist for advice.


Why do I have to answer questions before I can buy this product?

You do not need a prescription for Nytol Liquid; however, you will be asked to complete a short medical questionnaire by your Chemist 4 U pharmacist before we can take your order. This includes some simple questions that all pharmacies legally are required to ask before supplying this kind of product. This helps our pharmacy team to be sure that this product is the best choice for you.


When should this product not be used?

Nytol Liquid is not suitable for those who are allergic to diphenhydramine or any of the other listed ingredients. You should not use this product if you have a peptic ulcer or any blockage between your stomach and small intestine. Speak to your doctor or pharmacist before using this product if you have:

  • A condition called Myasthenia Gravis, which causes abnormal muscle function
  • Epilepsy or suffer from seizures
  • Asthma, bronchitis, or Chronic Obstructive Pulmonary Disease (COPD)
  • Narrow-angle glaucoma
  • An enlarged prostate
  • Difficulty urinating
  • Moderate to severe liver or kidney problems
  • If you are elderly, especially if you suffer from confusion


Does this medicine contain E numbers?

Nytol Liquid does contain E numbers, which in this case are mostly used as preservatives and are a type of ingredient known as parahydroxybenzoates. The parahydroxybenzoates used in this product are:

  • Methyl E218
  • Ethyl E214
  • Propyl E216
  • Butyl

This product also contains one E number which is used as a colouring, which is caramel E150.


Is this product sugar-free?

Nytol Liquid contains 1.66g of sucrose in every 5ml. If you or your child have diabetes or an intolerance to some sugars, you should speak to your doctor or pharmacist before taking this product.


Does Nytol Liquid have any side effects?

Like all medications, Nytol Liquid can have side effects, although not everyone will experience them. These side effects include signs of a severe allergic reaction, such as:

  • Difficulty breathing or shortness of breath, swelling of the face, mouth, throat, tongue, etc.
  • Itchy, raised rash (hives)

If you notice any signs of an allergic reaction, stop use and seek medical assistance immediately. You should also speak to your doctor right away if you experience:

  • Fast or irregular heartbeat
  • Fits, difficulty making or controlling movement

Other side effects you may experience include:

  • Drowsiness, tiredness, sedation, dizziness, feeling unsteady, finding it difficult to concentrate
  • Dry mouth
  • Fatigue
  • Feeling your heartbeat (palpitations)
  • Headache, pins and needles
  • Depression, sleeplessness
  • Confusion, increased energy, nervousness, restlessness, these effects may be more common in the elderly
  • Difficulty urinating or being unable to pee
  • Thicker bronchial mucus (phlegm)
  • Blurred vision
  • Feeling sick, stomach problems
  • Muscle twitching

If you experience these or any other side effects while using this product, speak to your doctor or pharmacist as soon as possible. For more information about reporting the side effects of medication, please see the MHRA’s Yellow Card Scheme.


How to store this product

Store in a cool, dry place which is below 25 degrees C. Do not use this product if the expiry date printed on its original packaging has passed. Keep out of sight and reach of children.


Important Information

This product is a medicine; make sure to speak to your doctor or Chemist 4 U pharmacist before taking this product if you have an underlying medical problem or are taking any other medicine or complementary therapy. If your symptoms get worse or continue after taking this product, contact us or your doctor. For medical services in your area, please refer to https://www.nhs.uk

If you are pregnant, trying to become pregnant, or breastfeeding, speak to your doctor or our pharmacist before taking this product. If you suffer from any allergies, ask your doctor or our pharmacist if this medicine is right for you.

Store all medicines out of sight and reach of children.

Please read the included leaflet carefully before using this product.

Please contact your GP if appropriate regarding this product.


Helpful Advice on Medication Restrictions & Addiction

For further information on our medication restrictions policy, please click here.

If you are concerned about addiction of 'over the counter' medication we urge you to visit the below links for professional help and advice:


  • The active substance is diphenhydramine hydrochloride, 10mg in 5ml.

    The other ingredients are: purified water, sucrose, sodium saccharin, propylene glycol, glycerin, parahydroxybenzoates (methyl E218, ethyl E214, propyl E216 & butyl), caramel flavouring, colouring (caramel E150).

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