Dymista Nasal Spray Suspension

Buy Dymista nasal spray

You can buy Dymista nasal spray as long as it's been approved and prescribed by one of our clinicians.

Dymista is a prescription-only treatment for moderate to severe allergic rhinitis when other nasal sprays haven't worked well enough.

What is Dymista nasal spray used for?

Dymista is used to treat allergies, like:

• hay fever
• dust mites
• pet dander
• mould

It helps to relieve symptoms like:

• sneezing
• a blocked, runny, or itchy nose
• postnasal drip

How does Dymista nasal spray work?

Dymista nasal spray contains two medicines that work together to help you feel more comfortable.

The first is azelastine, an antihistamine that blocks histamine, the chemical your body releases during an allergic reaction. This helps to ease symptoms like sneezing, itching, and a runny nose.

The second is fluticasone, a steroid that reduces swelling and inflammation inside your nose, helping with congestion. Because they tackle your symptoms from two different angles at the same time, they work better together than either medicine would on its own.

How long does Dymista take to work?

Since Dymista contains an antihistamine, it gets to work very quickly.

How long does Dymista stay in your system?

The two ingredients in Dymista are processed by your body at different rates. Azelastine, the antihistamine, has a half-life of around 22 hours, while fluticasone, the steroid, is mostly out of your system within 3-4 hours, with very small amounts remaining after 7-8 hours. 

Everyone is slightly different, and factors like your age, metabolism, and overall health can all influence how quickly your body processes the medicine.

How to use Dymista nasal spray

Always use Dymista nasal spray exactly as your doctor or pharmacist has told you.

Preparing your spray

• Shake the bottle gently for five seconds by tilting it upwards and downwards, then remove the protective cap.
• Before using your spray for the first time, you will need to prime the pump by squirting it into the air.
• To prime, place two fingers on either side of the spray pump and your thumb on the bottom of the bottle.
• Press down and release the pump six times until a fine mist appears.
• Your pump is now primed and ready to use.
• If you have not used your spray for more than seven days, re-prime the pump once by pressing down and releasing it.

Using your spray

Shake the bottle gently for five seconds by tilting it upwards and downwards, then remove the protective cap.

• Blow your nose gently to clear your nostrils.
• Tilt your head downwards towards your toes, do not tilt it backwards.
• Hold the bottle upright and carefully insert the spray tip into one nostril.
• Close your other nostril with your finger, press down once firmly and sniff gently at the same time.
• Breathe out through your mouth.
• Repeat in your other nostril.
• Breathe in gently and keep your head tilted downwards after using the spray, as this stops the medicine reaching your throat and causing an unpleasant taste.
• After each use, wipe the spray tip with a clean tissue or cloth and replace the protective cap.
• Do not prick the nozzle.

How many times a day can you use Dymista nasal spray?

Use Dymista twice a day, once in the morning and once in the evening, with one spray into both nostrils each time. Do not exceed this amount. For the best results, you should use Dymista consistently, as advised.

How much does Dymista cost?

At the time of writing, prescription-strength Dymista is available in the following pack sizes:

• 1 pack: £19.79
• 2 pack: £37.99
• 3 pack: £55.99

Dymista nasal spray side effects

Like all medicines, Dymista can cause side effects, although not everybody gets them.

Very common side effects (may affect more than 1 in 10 people):

• nosebleed

Common side effects (may affect up to 1 in 10 people):

• headaches
• a bitter taste in your mouth
• an unpleasant smell

How long do Dymista side effects last?

Most side effects from Dymista are mild and tend to settle down on their own as your body adjusts. However, if any side effects persist, feel severe or are causing you concern, it's always best to speak to your doctor or pharmacist.

Managing your side effects

Here are a few simple tips to help you manage any side effects you may experience while using Dymista:

• Nosebleed: Blow your nose gently before using the spray and hold the bottle upright and aim it away from the centre of your nose. If nosebleeds are frequent or heavy, speak to your prescriber.
• Headaches: Stay well-hydrated and consider over-the-counter pain relief like paracetamol to ease any discomfort.
• Bitter taste: Keep your head tilted downwards while using the spray and have a soft drink a few minutes afterwards to help ease the taste.
• Unpleasant smell: This is usually temporary and should pass on its own shortly after using the spray.

When to avoid Dymista nasal spray

Don't use Dymista if you're allergic to azelastine, fluticasone, or any of the other listed ingredients. If you're pregnant or breastfeeding, speak to your prescriber before using this spray.

This spray isn't suitable for children under the age of 12. Please note that we can't prescribe Dymista to anyone under the age of 18 from our clinic.

Dymista has a minor influence on your ability to drive or use machinery. In rare cases, you may experience fatigue or dizziness, either due to your allergies or as a result of using Dymista.

If this happens, avoid driving or operating machinery until you feel better. It's also worth knowing that drinking alcohol may make these effects worse.

Dymista interactions

Let your doctor or pharmacist know if you're taking any other medicines, including those bought without a prescription. Some medicines can increase the effects of Dymista, so they may want to monitor you more closely. This includes:

• medicines for HIV, like ritonavir and cobicistat
• medicines for fungal infections, like ketoconazole

Alternatives to Dymista nasal spray

If Dymista isn't quite right for you, there are other options available to help manage your hay fever or allergy symptoms. It’s important to note that some of these treatments are only available after a short consultation.

Dymista alternatives include:

• Generic or unbranded Dymista: Azelastine & fluticasone nasal spray contains the same active ingredients as Dymista and works in the same way but may be available at a lower cost.
• Other dual-action nasal sprays: Dymista Control is another version of Dymista that you can buy over-the-counter without a prescription. Ryaltris Nasal Spray also contains both an antihistamine (olopatadine) and a steroid (mometasone).
• Steroid nasal sprays: Sprays like fluticasone or mometasone help to reduce inflammation and congestion inside the nose. Examples include fluticasone nasal spray or its branded alternatives Avamys, Flixonase, or Pirinase, or mometasone nasal spray or the brands Nasonex or Clainaze.
• Antihistamine nasal sprays: Rhinolast contains azelastine and provides fast-acting relief against allergy symptoms.
• Oral antihistamines: Tablets like cetirizine (Benadryl Allergy), loratadine (Clarityn), or fexofenadine (Allevia, Histallay, Treathay) are popular and convenient options, and they’re unlikely to make you feel drowsy.

Frequently asked questions about Dymista nasal spray

Why is Dymista so expensive?

Dymista combines two active ingredients, azelastine and fluticasone, into one convenient spray. The cost reflects the dual-action formula, which is clinically proven to work better than either ingredient on its own.

Is Dymista a steroid?

Dymista contains a corticosteroid, or steroid, called fluticasone propionate. But it also contains an antihistamine called azelastine, so it’s actually a combination of both.

Does Dymista help with post-nasal drip?

Yes, Dymista can help with post-nasal drip. Because it reduces inflammation and helps to control the allergic response inside your nose, it can reduce the excess mucus that causes that uncomfortable dripping sensation at the back of your throat.

Is Dymista good for a sinus infection?

Dymista is designed to treat allergies rather than sinus infections. While it may help to ease some of the congestion and inflammation associated with a sinus infection, it won’t treat the infection itself.

If you think you have a sinus infection, it's best to speak to your GP or pharmacist who can advise on the most appropriate treatment for you.

Can you buy Dymista over the counter?

This Dymista product is only available with a prescription. However, Dymista Control is available to buy over-the-counter without a prescription. If you're unsure which option is right for you, our pharmacists will be happy to help.

Can you take antihistamines with Dymista?

Dymista already contains an antihistamine called azelastine, so taking additional antihistamines alongside it may not be necessary and could increase the risk of side effects like drowsiness.

Always speak to your prescriber before taking another antihistamine alongside Dymista.

Sources

· Patient Information Leaflet. MHRA. [Accessed 2nd March 2026].

· Why Have I Been Prescribed Dymista? (2024). Dymista. [Accessed 2nd March 2026].

· Dymista FAQs. (2024). Dymista. [Accessed 2nd March 2026].

· Azelastine. ScienceDirect. [Accessed 2nd March 2026].