Orlistat (Generic Xenical) Capsules

Based on 26 reviews

Available in pack sizes of 42, 84, 168 and 252 capsules

The treatment is inclusive of consultation, private prescription & medicine delivery
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Laura Henderson - Medical Content Writer
Laura Henderson
Medical Content Writer
James O'Loan - CEO & Superintendent Pharmacist
James O'Loan
CEO & Superintendent Pharmacist

Buy Orlistat Online

Orlistat is a weight loss medication that can work with your diet to help you to meet your weight loss goals. If you have a BMI of 30 or over and are looking for something that will help make your healthy diet work a little harder, orlistat could be the product for you.


How orlistat works

Orlistat works by clinging to the enzymes in your digestive system and keeping them from absorbing and digesting the fat that’s in your food. This helps to reduce the amount of fat you absorb by around a third, letting the undigested fat pass from your body instead. This helps you to meet your weight loss goals by making your healthy diet choices go further.



Follow the directions given to you by your doctor carefully. The usual dose you will be prescribed is one 120mg orlistat capsule three times a day, one with every meal. You can take your capsule immediately before, during, or up to one hour after a meal. Swallow the capsule with water. Your doctor will usually stop treatment if you have not lost at least 5% of your body weight after 12 weeks of taking this product.


Side Effects

Like all medication, orlistat can have side effects, although not everyone will experience them. The most common side effects of this product include:

  • Headaches
  • Abdominal pain or discomfort
  • Urgent or increased need to poo
  • Flatulence (wind) with or without discharge
  • Oily discharge, oily or fatty stools
  • Liquid stools
  • Low blood sugar levels, which may be experienced by those with type 2 diabetes
  • Upper respiratory infections
  • Flu
  • Rectal pain or discomfort
  • Soft stools
  • Incontinence (stools)
  • Bloating, which may be experienced by those with type 2 diabetes
  • Tooth or gum disorder
  • Irregularity of your menstrual cycle
  • Tiredness
  • Anxiety
  • Lower respiratory infections
  • Urinary tract infections

For a full list of potential side effects, please see the patient information leaflet included with your medication. If you experience these or any other side effects while using this product, stop use and speak to your doctor or pharmacist. For more information about reporting the side effects of medication, please see the MHRA’s Yellow Card Scheme.



Orlistat is not suitable for use in children. Do not use this product if you are allergic to orlistat or any of the other listed ingredients. Speak to your doctor or pharmacist before taking this product if you have kidney problems. Do not take this product if you have:

  • Chronic malabsorption syndrome
  • Cholestasis (liver disorder)


Pregnancy and breastfeeding

If you’re pregnant or breastfeeding, you should not take orlistat. If you’re concerned about your weight during pregnancy or are unsure which medication is safe for you at this time, speak to your doctor or pharmacist for advice.


Other medication

If you’re taking any other medication, including those obtained without a prescription, you should speak to your doctor or pharmacist before taking this product. This especially applies if you are taking:

  • Anticoagulants, or blood thinners, such as warfarin
  • Ciclosporin
  • Iodine salts and/or levothyroxine, which are both used to treat thyroid gland problems
  • Amiodarone, which is used to treat irregular heartbeat
  • Medications used to treat HIV
  • Antiepileptics
  • Acarbose, which is used to treat type 2 diabetes


Important information

This product is a medicine; make sure to speak to your doctor or Chemist 4 U pharmacist before taking this product if you have an underlying medical problem or are taking any other medicine or complementary therapy. If your symptoms get worse or continue after taking this product, contact us or your doctor. For medical services in your area, please refer to https://www.nhs.uk

If you are pregnant, trying to become pregnant, or breastfeeding, speak to your doctor or our pharmacist before taking this product. If you suffer from any allergies, ask your doctor or our pharmacist if this medicine is right for you.

Store all medicines out of sight and reach of children.

Please read the included leaflet carefully before using this product.

Please contact your GP if appropriate regarding this product.



Store in a cool, dry place which is below 25 degrees C. Do not use if the expiry date printed on the original packaging has passed. Keep out of sight and reach of children.

Orlistat (Generic Xenical) Capsules Reviews

By Sarah,
January 30, 2024
Polycystic ovaries, so store fat out of every thing eat, Also can only take two a day because of the medication I’m on, but I’m happy that I’ve lost 6lbs since I started using them so I will carry on while they still, As before that, I was just continually putting on weight
By Cindy Dyball,
January 23, 2024
Works really well for me
By Sarah Bawden,
August 01, 2023
Not received
By Isabella,
June 13, 2023
working so far lost a few pounds already
By Vizzion _Sway,
April 25, 2023
These really work for me as I struggle with other diets.

Advice & Guides

Do weight loss pills really work?

When it comes to losing weight, people want to do it quickly. Lots of exercise, strict diet, and supplements, including weight loss pills, are usually taken in the hope that this will speed up the process.

Read More
Frequently Asked Questions

Do I have to be a certain BMI to take Orlistat?

Orlistat is designed to be used by those who have a BMI of 30 or over, or those with associated risk factors (such as diabetes) who have a BMI of 28 or over.

If you’re not sure what your BMI is, you can use an online calculator to find out whether this product is suitable for you.

If you’re not sure whether you should be taking orlistat, always speak to your doctor or pharmacist and get their advice.

Do I have to change my diet while I’m taking orlistat?

Orlistat is at its best when used alongside a calorie-controlled, low-fat diet.

For best results, you should aim to have an average of 30% fat in your diet, which is spread across each of your meals evenly.

If you eat food with higher fat content, then you may be more likely to experience side effects such as oily, fatty stools, or flatulence with discharge.

How long does orlistat take to work?

Orlistat will get to work reducing the amount of fat absorbed from your food right away.

However, this doesn’t mean you’ll see weight loss results immediately.

Weight loss is always a slow process and as much as this treatment can help, how quickly you shed the pounds will ultimately be decided by what you eat and how much exercise you do.

Will this medication affect my birth control?

Orlistat usually won’t affect contraception, but some of the potential side effects can affect oral birth control like the mini pill or combined pill.

If you do take oral contraception you should consider using a second method of contraception, like condoms, when you first start your treatment.

One of the potential side effects of orlistat is diarrhoea, and if you have severe diarrhoea it can mean that your contraceptive pill won’t be absorbed properly in your system.

If this happens, you won’t be effectively protected from pregnancy, which is why you would need to use a second method of contraception.

If you have severe diarrhoea after taking this medication you should speak to your doctor or pharmacist as soon as you can, as this treatment may not be right for you.

Do I need a prescription for this medication?

You do need a prescription for this medication in the UK.

Our healthcare professionals can provide prescriptions if they think this treatment would be right for you and your condition.

When you click the button which reads “Start Consultation” at the top of this page, you’ll see a short questionnaire set up by our healthcare team which is designed to help them understand your medical needs.

Just like an in-person consultation with your GP, our doctors will assess your answers to their questions and write a prescription for the treatment they think will be best for you.

You’ll then be able to pay for your medication and we’ll send it out to you quickly and in discreet packaging.

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