Orlos (Orlistat) 60mg Weight Loss Aid - 84 Capsules - 3 Pack

Based on 28 reviews
Save 15%
RRP  £72.57
check In stock
-
+
Express 1-2 Days (Royal Mail Tracked 24)
Order in the next 00 :00 :00 to get it tomorrow * using Express 1-2 Days (Royal Mail Tracked 24)
*95% of orders using express delivery are delivered next day

Save With Multipacks:

Choose your multipack... chevron-down
Laura Henderson - Medical Content Writer
Laura Henderson
Medical Content Writer
12/12/2024
11/12/2026
James O'Loan - CEO & Superintendent Pharmacist
James O'Loan
CEO & Superintendent Pharmacist
2084549
12/12/2024

Buy Orlos (Orlistat) 60mg Weight Loss Aid Capsules 

Orlos (Orlistat) 60mg Weight Loss Aid Capsules is a weight loss medication that can be used alongside a low-fat diet and a healthy lifestyle to help you lose more weight than dieting alone. 

Orlos doesn’t do all of the work for you, but it helps to make your hard work count more. For example, if you lose 4lb by dieting alone, Orlos can help you lose 2lb more! 

If you have a BMI of 28 or over and start following a reduced-calorie, low-fat diet, Orlos could help you meet your weight loss goals.

 

How Orlos (Orlistat) 60mg Weight Loss Aid Capsules work

Orlistat is the active ingredient in Orlos capsules, and it works by changing how your body absorbs fat.

Orlistat stops a quarter of the fat in your food from being absorbed into your body so it can be passed with your stools. When combined with a reduced-calorie, low-fat diet, this can help you lose weight by reducing your overall fat intake.

 

Directions

Always take Orlos exactly as described in the patient information leaflet or as your doctor / Chemist4U pharmacist has told you. 

Take 1 Orlos capsule 3 times a day. Swallow your capsule with a sip of water during your meal, or take it within an hour after your meal.

For the best results, you should spread your tablets evenly throughout the day and after a balanced meal, such as breakfast, lunch, and dinner. 

If you skip a meal or your meal contains no fat, do not take your Orlos capsule. It will not work if there is no fat in your meal.

Do not take more than 3 capsules a day. 

You shouldn’t take Orlos for more than 6 months. As long as you are making positive changes to your diet and exercise, this should be enough to kick-start your weight loss. 

If you haven’t lost weight after taking these capsules for 12 weeks, ask your doctor or pharmacist for advice.

 

Side effects

Like all medicines, Orlos may cause side effects in some people, but these won’t affect everybody. Common side effects of this product may include:

 

  • Wind, with or without oily spotting 
  • Sudden bowel motions 
  • Oily discharge, fatty or oily stools 
  • Soft stools 
  • Stomach pain
  • Incontinence 
  • Runny stools 
  • More frequent bowel movements 
  • Anxiety 

 

If you experience any side effects, including any not included in the patient information leaflet, you can report them using the MHRA Yellow Card Scheme.

 

Serious side effects

Seek emergency medical attention if you notice any signs of a severe allergic reaction, symptoms of which include swelling of the face and throat, skin rash, breathing difficulties and/or loss of consciousness. 

If you experience any of the following side effects, stop taking this medication immediately and seek medical advice straight away: 

 

  • Bleeding from the back passage 
  • Diverticulitis (inflammation of the large intestine). Symptoms may include severe abdominal pain, which sometimes radiates towards the back, alongside a fever, nausea and vomiting
  • Skin blistering 
  • Severe stomach pain caused by gallstones 
  • Hepatitis (inflammation of the liver). Symptoms can include yellowing of the skin or whites of the eyes, itching, dark-coloured urine, stomach pain and liver tenderness that is sometimes accompanied by a loss of appetite 
  • Oxalate nephropathy (build-up of calcium oxalate, which may lead to kidney stones) 

 

Warnings

Orlos may be unsuitable for certain people. Do not take these capsules if you are allergic to any of the ingredients or if:

 

  • You have cholestasis 
  • You have problems absorbing food (chronic malabsorption syndrome)

 

Talk to your doctor or Chemist4U pharmacist before taking this medicine if you have diabetes or kidney disease.

 

Using/taking other medicines

If you are taking or have recently taken any medication, including medication obtained without a prescription, talk to your GP or pharmacist before taking this medication.

Do not take Orlos if you are taking the following medication:

 

  • Ciclosporin (used after organ transplants, for severe rheumatoid arthritis and some severe skin conditions) 
  • Warfarin or other medications used to thin the blood
  • Acarbose (anti-diabetic drug)

 

The oral contraceptive pill may be less effective if you get severe diarrhoea whilst taking Orlos. We recommend using additional contraception. 

You must tell your healthcare provider if you are taking the following medication:

 

  • Amiodarone (used for heart rhythm problems) 
  • The thyroid medication, levothyroxine 
  • Any medication used for epilepsy 
  • Medicines used to treat HIV 
  • Medicines for depression, psychiatric disorders or anxiousness
  • Medication for high blood pressure 
  • Medication for high cholesterol 

 

When taking Orlos, you are advised to take a multivitamin daily. Orlos can lower the levels of some vitamins absorbed by the body. You should take the multivitamin at bedtime, when you will not be taking Orlos, to ensure that the vitamins are absorbed.

 

Age restrictions 

This product is unsuitable for anyone under 18 years old.

 

Pregnancy and breastfeeding

Do not take Orlos if you are pregnant or breastfeeding. If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, you must ask your doctor or Chemist4U pharmacist for advice before taking any new medicine. 

 

Food and drink

Try to avoid eating any high-fat meals when you are taking Orlos.

 

Storage information

Store in a cool, dry place out of sight and reach of children. Do not use after the expiry date, referring to the last day of the month stated on the packaging. Do not throw away any medicines via wastewater or household waste.

 

Important information

This product is a medicine; make sure to speak to your doctor or Chemist4U pharmacist before taking this product if you have an underlying medical problem or are taking any other medicine or complementary therapy. If your symptoms get worse or continue after taking this product, contact us or your doctor. For medical services in your area, please refer to the NHS website. 

If you are pregnant, trying to become pregnant, or breastfeeding, speak to your doctor or Chemist4U pharmacist before taking this product. If you suffer from any allergies, ask your doctor or Chemist4U pharmacist if this medicine is right for you.

Store all medicines out of sight and reach of children.

Please read the included leaflet carefully before taking this product.

Please contact your GP if appropriate regarding this product.

 

Find similar products

Orlos (Orlistat) 60mg Weight Loss Aid - 84 Capsules - 3 Pack Reviews

white-star white-star white-star white-star
By Gail Absolom,
October 07, 2025
I find these work for me and my weight loss. Alongside a healthy diet
white-star white-star white-star white-star white-star
By Mrs Victoria John,
July 01, 2025
Good choice
white-star white-star white-star white-star white-star
By Kasia K,
July 30, 2024
Brilliantly and quick service, I love it
white-star white-star white-star white-star white-star
By James Bernasconi,
May 14, 2024
Perfect very much needed
white-star white-star white-star white-star white-star
By Patricia Scappaticci,
October 10, 2023
Effective and well priced product

Advice & Guides

Where is the best place to inject Mounjaro?

When it comes to injecting Mounjaro, the best place is whichever approved spot feels most comfortable for you. Everyone’s different, and the right choice can depend on a few factors, like whether you want to minimise side effects, find the least painful area, or have someone else administer the injection...
Read More

BMI Calculator

Find your BMI to better understand your weight and whether you might be eligible for weight loss treatment.
Read More

Obesity Statistics Report 2025

Obesity is a chronic and complex condition that can have significant impacts on people’s health, life expectancy, and quality of life, not to mention the wider effects on society and the economy. By 2040, it’s estimated that more than 70% of people across the UK could be classed as overweight...
Read More

What is BMR? How do you calculate yours?

Your basal metabolic rate (BMR) is the number of calories your body burns at rest to keep you alive - powering your heart, brain, breathing, and digestion. Knowing your BMR helps you understand your body’s energy needs so that you can make more informed choices about nutrition, exercise, and weight...
Read More

BMR Calculator

Calculate your BMR: Find the average amount of calories you need based on your lifestyle. BMR isn't used to check eligibility for weight loss treatment, but you can use our BMI calculator. BMR Calculator * { margin: 0; padding: 0; box-sizing: border-box; } body { font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI...
Read More

Mounjaro Heartburn: Everything You Need to Know

Heartburn is a common symptom that some people experience when taking Mounjaro. It happens because the treatment slows digestion, which can increase the chance of acid reflux. Here, we explain why it occurs, how long it lasts, and what you can do to manage it. Three key takeaways Mounjaro can...
Read More

Menopause and Weight Loss

Weight gain around menopause is common due to hormonal changes and a slower metabolism. However, with the right diet, lifestyle, and treatments like HRT or weight loss injections, you can manage your weight and improve your well-being. Here, we’ll cover everything you need to know about weight loss during menopause...
Read More

Mounjaro Supplements

You may be considering taking supplements while you’re on Mounjaro but you likely won't need to. It's possible to get everything you need from a well-rounded diet.  But if reduced appetite, or side effects like nausea, heartburn, or indigestion are making it challenging to get all the nutrients you need...
Read More
© 2025 Chemist4U. Innox Trading Ltd, 1 Penketh Place, Skelmersdale, Lancashire, WN8 9QX, GB. All rights reserved. Registered and regulated UK pharmacy with the GPhC (registered premises 9012464). Registered in England No. 07262043 | VAT Registration No. GB140138454