Night Nurse Cold Remedy – 160ml

Based on 21 reviews
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Laura Henderson - Medical Content Writer
Laura Henderson
Medical Content Writer
James O'Loan - CEO & Superintendent Pharmacist
James O'Loan
CEO & Superintendent Pharmacist

What is Night Nurse Liquid?

Night Nurse Liquid is a cold and flu medicine that you can take before you go to bed at night. It helps to ease your symptoms and helps you to get a good nights sleep as you recover from that cold. Night Nurse syrup is ideal for adults and children over 16 who have a cold or the flu and prefer taking liquid medicines to tablets.

How will the ingredients in Night Nurse Liquid ease my cold and flu symptoms?

Night Nurse Liquid contains three active ingredients which work together to treat different symptoms of cold and flu:

  • Paracetamol 1000mg - A popular everyday painkiller which can also bring down a high temperature or fever

  • Promethazine hydrochloride 20mg - An antihistamine which dries up a runny nose and helps you to get to sleep

  • Dextromethorphan hydrobromide 15mg - a cough suppressant which helps to ease dry or tickly coughs

Do I have a cold or the flu?

Cold and flu are very similar conditions, but there are a couple of differences you can look for if you’re trying to determine whether you have one or the other:

  • Sudden onset of symptoms - The flu will come on much more suddenly than a cold

  • Fatigue - If you have the flu you will usually be too exhausted to perform your everyday activities, but if you have a cold you’ll usually be able to soldier on despite your symptoms

  • Nose and throat symptoms - A cold will mainly affect your nose and throat, the flu will affect more than that

Can I use this syrup if I’m pregnant or breastfeeding?

If you’re pregnant or breastfeeding you should not take Night Nurse liquid. This product contains alcohol, which you should not have at all during pregnancy, and should limit when you’re breastfeeding.

Can I drive after taking this product?

Night Nurse liquid can cause dizziness, drowsiness, blurred vision, difficulty concentrating, or movement difficulties. If you experience any of these symptoms after taking this product, do not attempt to drive or use any tools or machinery until you are certain that you’re safe to do so. 

Can I drink alcohol while I’m taking this medicine?

You should not drink alcohol when you’re taking Night Nurse liquid. This product also contains alcohol, with each dose containing the equivalent of 72ml of beer or 30ml of wine. This could make this product unsuitable for those with alcoholism, children, or high-risk patients, such as those with epilepsy or liver disease.

Can I take this product if I’m taking other medications?

If you’re taking other medication, including those obtained without a prescription, you should speak to your doctor before taking Night Nurse syrup. This especially applies if you are taking:

  • Metoclopramide or domperidone, which are used for nausea and vomiting

  • Colestyramine, which is used to lower blood cholesterol

  • Medicines which give you blurred vision, dry mouth, or drowsiness

  • Blood thinners, which are also known as anticoagulants, such as warfarin

  • Quinidine or amiodarone, which are used to control heart rhythm

  • Medicines for anxiety or depression, e.g. SSRIs or tricyclic antidepressants

  • Medicines to help you to sleep

Do not take this medicine if you are already taking:

  • Any other medications which contain paracetamol

  • Any other cough or cold medicines

  • Any other antihistamines, including those used on the skin

Can I take Night Nurse Liquid and Day Nurse Liquid at the same time?

You can take Night Nurse Liquid and Day Nurse Liquid at the same time to ease your cold and flu symptoms. However, you will need to make sure that you only take 3 doses of Day Nurse a day, and leave at least 4 hours between taking your final daily dose of Day Nurse and your bedtime dose of Night Nurse. If you’re planning on doing this, we’d recommend speaking to your doctor or pharmacist first, to make sure that this combination is safe and suitable for you.

What is the dosage of this liquid medicine?

Take one 20ml dose of Night Nurse Liquid before bedtime. Do not take this medicine if you have already taken 4 doses of paracetamol containing product in one day. Do not take for more than 3 days.

When should this syrup not be used?

Night Nurse Liquid is not suitable for use in children under the age of 16. Do not take this product if you are allergic to paracetamol, promethazine hydrochloride, dextromethorphan hydrobromide, or any of the other listed ingredients. Do not take this syrup if you have:

  • A chest infection, worsening asthma, or severe respiratory problems

  • Taken Monoamine Oxidase Inhibitors (MAOIs) for depression within the last 2 weeks

  • Are having a pregnancy test taken with your urine

Speak to your doctor or pharmacist before taking this product if you:

  • Suffer from alcoholism, or have liver disease or epilepsy, as this product contains alcohol

  • Have symptoms which are accompanied by high temperature, skin rash, or persistent headache

  • Have heart, kidney, or liver problems

  • Have glaucoma, epilepsy, difficulty passing urine, prostate problems

  • Have a chronic or persistent cough with excessive phlegm or respiratory problems

  • Have diabetes mellitus, as each 20ml dose of this medicine contains 12.8g of glucose

  • Are on a sodium controlled diet, as each 20ml dose of this medicine contains 37mg of sodium

  • Are elderly and suffer from confusion

Does Night Nurse Liquid have any side effects?

Like all medications, Night Nurse Liquid can have side effects, although not everyone will experience them. If you experience any of the following side effects, stop use and speak to a doctor right away:

  • Allergic reactions which may be severe, e.g. skin rash, itching, swelling of the mouth, throat, face, etc., shortness of breath

  • Skin rash, peeling, mouth ulcers

  • Breathing problems, which may be more likely if you have experienced them when taking other painkillers, such as ibuprofen or aspirin

  • Unexplained bruising or bleeding

  • Confusion, feeling restless, sweating, shivering, shaking, sudden muscular jerks, increased blood pressure

  • Difficulty passing urine

  • Nausea, vomiting, stomach ache, sudden weight loss, loss of appetite, yellowing of the eyes and skin

  • Restlessness, nervousness, feeling irritable, increased energy, sleep disturbances, especially in children

Other side effects you may experience include:

  • Drowsiness

  • Dizziness

  • Blurred vision

  • Difficulty concentrating

  • Unsteadiness

  • Clumsiness

  • Headache

  • Dry mouth

If you experience these or any other side effects while using this product, stop use and speak to your doctor or pharmacist. For more information about reporting the side effects of medication, please see the MHRA’s Yellow Card Scheme.

How to store this product

Store in a cool, dry place. Do not use this product if the expiry date printed on the original packaging has passed. Keep out of sight and reach of children.


Why do I need to answer questions to buy this product?

You do not need a prescription for Night Nurse Liquid, however, you will be asked to complete a short medical questionnaire by your Chemist 4 U pharmacist before we can take your order. This includes some simple questions that all pharmacies legally are required to ask before supplying this kind of product. This helps our pharmacy team to be sure that Night Nurse is the best choice for you.


More Information

This product is a medicine; make sure to speak to your doctor or Chemist 4 U pharmacist before taking this product if you have an underlying medical problem or are taking any other medicine or complementary therapy. If your symptoms get worse or continue after taking this product, contact us or your doctor. For medical services in your area, please refer to

If you are pregnant, trying to become pregnant, or breastfeeding, speak to your doctor or our pharmacist before taking this product. If you suffer from any allergies, ask your doctor or our pharmacist if this medicine is right for you.

Store all medicines out of sight and reach of children.

Please read the included leaflet carefully before using this product.

Please contact your GP if appropriate regarding this product.


Helpful Advice on Medication Restrictions & Addiction

For further information on our medication restrictions policy, please click here.

If you are concerned about addiction to 'over the counter' medication, we urge you to visit the below links for professional help and advice:

Night Nurse Cold Remedy – 160ml Reviews

By Alan,
February 27, 2024
It works very well
By Mrs Christine Bennetta,
February 21, 2024
By Tanya Cathrow,
January 30, 2024
Our best product when someone is ill. Really excellent, helps unblock your nose and aids sleep.
By Janet,
January 23, 2024
Good product for helping with cold symptoms at night.
By Matt,
December 12, 2023
Definitely one of the best remedies for flu like symptoms *****

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