Ovesse 1mg/g Vaginal Cream - 15g Tube + Applicator

Buy Ovesse 1mg/g Vaginal Cream – 15g Tube + Applicator

Ovesse vaginal cream is a local hormone replacement treatment used to relieve vaginal symptoms caused by menopause. It contains estriol, a form of oestrogen that works directly in the vaginal area to restore moisture and comfort.

Ovesse is designed for women experiencing symptoms linked to low oestrogen levels, like dryness, irritation, or discomfort during sex.

Unlike systemic HRT (which affects your whole body), Ovesse works locally, meaning the hormone is applied directly where it’s needed. This helps reduce symptoms while limiting the amount of hormone that enters your bloodstream.

What is Ovesse vaginal cream used for?

Ovesse is used to treat vaginal atrophy, also known as genitourinary syndrome of menopause (GSM).

This condition happens when oestrogen levels drop, leading to thinning, dryness, and inflammation of vaginal tissues.

Ovesse may help relieve:

• vaginal dryness
• itching or irritation
• pain during sex
• burning or discomfort
• recurrent urinary symptoms linked to menopause

How long does it take Ovesse cream to work?

You may start to notice improvement within a few weeks, but it can take up to 8–12 weeks for the full benefits.

Using the cream regularly as directed helps restore vaginal tissue over time, rather than providing instant relief.

Benefits of Ovesse cream

• Designed for menopausal and postmenopausal symptoms.
• Comes with an applicator for easy, targeted use.
• Restores natural moisture and elasticity.
• Reduces dryness and irritation.
• Improves comfort during sex.
• Helps maintain healthy vaginal tissue.
• Can reduce urinary symptoms linked to menopause.
• Suitable if you cannot or prefer not to use systemic HRT (though it can also be used alongside HRT).

How to use Ovesse vaginal cream

Ovesse is applied inside the vagina using the applicator provided. You should:

• Wash your hands before use
• Fill the applicator with the prescribed amount of cream
• Gently insert the applicator into the vagina
• Press the plunger to release the cream
• Remove and clean the applicator after use

Ovesse cream is usually applied once a day at first. It’s best to use the cream at night to allow for better absorption.

As your symptoms improve, you can potentially use it less frequently, for example twice a week. However, you should continue using the treatment for as long as your clinician has recommended.

Always follow the instructions provided by your healthcare professional or the patient information leaflet.

Potential Ovesse side effects

Ovesse is generally well tolerated, but some side effects can occur, particularly when starting treatment. Common side effects include:

• mild vaginal irritation
• itching
• burning sensation
• increased vaginal discharge

These are usually temporary and improve as your body adjusts.

Seek medical advice if you experience:

• persistent vaginal bleeding
• severe irritation or pain
• signs of an allergic reaction (swelling, rash, difficulty breathing)

If you notice unusual symptoms, speak to your doctor or pharmacist.

When not to use Ovesse cream

Ovesse may not be suitable for you if you:

• have a history of oestrogen-sensitive cancers (e.g., breast cancer)
• have unexplained vaginal bleeding
• have untreated endometrial thickening
• are allergic to any of the ingredients

A healthcare professional will assess whether Ovesse is safe for you before recommending it.

Storage information

• Store below 25°C.
• Keep the tube tightly closed.
• Protect from heat and moisture.
• Keep out of reach of children.

Do not use after the expiry date.

Alternatives to Ovesse cream

If Ovesse is not suitable for you, there are other options available.

• vaginal tablets (pessaries)
• vaginal rings
• other estriol or estradiol creams

These work in a similar way but differ in how they are applied. Talk to your clinical or healthcare professional to decide which treatment options will work best for you,

If you’re looking for a non-hormonal alternative, you could consider:

• vaginal moisturisers
• water-based lubricants
• regular sexual activity (can help maintain tissue health)

There are also systemic treatments for menopause if you want to address more than vaginal atrophy alone:

• hormone replacement therapy (HRT) tablets or patches
• other prescription menopause treatments

Your healthcare provider can help you choose the most appropriate option based on your symptoms and medical history.

Frequently asked questions about Ovesse cream

Can I buy Ovesse over-the-counter?

Yes. Ovesse is available from pharmacies without a prescription following a consultation to ensure it's suitable for you.

Is Ovesse cream the same as estriol cream?

Yes. Ovesse contains estriol, a type of oestrogen. It's one of several estriol-based creams used to treat vaginal symptoms of menopause.

Can you use Ovesse if you are on HRT?

In some cases, Ovesse can be used alongside systemic HRT if vaginal symptoms persist. You should always speak to your doctor or pharmacist before combining treatments.

What are the symptoms of genitourinary syndrome?

Symptoms of genitourinary syndrome of menopause (GSM) can include:

• vaginal dryness
• irritation or itching
• pain during sex
• urinary urgency, discomfort, or recurrent urinary tract infections

These symptoms are caused by reduced oestrogen levels and can worsen over time without treatment.

What does vaginal atrophy feel like?

Vaginal atrophy often feels like dryness, tightness, or irritation in the vaginal area. You may also notice discomfort during sex or increased sensitivity.

These symptoms can affect your daily comfort and quality of life, but treatments like Ovesse can help restore normal function.

Sources

• Ovesse Vaginal Cream PIL. EMC. [Accessed 9 April 2026].
• Menopause. (2023). NHS. [Accessed 9 April 2026].
• Vaginal dryness. (2023). NHS. [Accessed 9 April 2026].
• Menopause: diagnosis and management (NG23). (2019). NICE. [Accessed 9 April 2026].