How to Deal With an Allergic Reaction 

Most allergic reactions are mild, and symptoms can be kept at bay with medications like antihistamines and nasal sprays. However, some allergies can be more serious, and even life-threatening, if not treated in time.  

We’ll walk you through how to deal with an allergic reaction, how long symptoms can last, and when you should seek medical help.

Three key takeaways 

  • Allergies are very common and usually mild.
  • Symptoms can vary hugely but are normally manageable using antihistamines.
  • Some symptoms indicate a more serious, anaphylactic reaction. We’ll look carefully at when you should seek urgent medical help.

Man having an allergic reaction

What causes an allergic reaction? 

“An allergic reaction happens when your immune system mistakes something that’s usually harmless, like pollen, dust or animal fur as a threat and produces antibodies in response.

“When you are exposed to the substance you are allergic to (allergen), your body releases chemicals including histamine that cause tissues in your body to swell and itch, which results in the signs of an allergic reaction. Symptoms vary from person to person, and even from attack to attack.”

Hanna Yusuf, Prescribing Pharmacist at Chemist4U

Hanna Yusuf, Prescribing Pharmacist

How long can an allergic reaction last? 

An allergic reaction can last anywhere from a few minutes or hours to several days. It depends on how severe your response is, and the kind of allergen you’ve been exposed to.

If you have a severe reaction, known as anaphylaxis, symptoms can last days, and will sometimes need extended medical attention.

What’s the difference between an allergic reaction and anaphylaxis? 

It’s not always easy to tell the difference between an allergic reaction and anaphylaxis. But a good rule of thumb is that an allergic reaction usually only affects one part of your body, while anaphylactic shock involves multiple organs.

Most doctors consider an allergic reaction to be anaphylaxis if it causes breathing difficulties, affects your heart rhythm, or affects your blood pressure. Healthcare professionals sometimes refer to these as the ABC symptoms.

If your symptoms affect your:

  • airway (swelling in the throat, tongue or windpipe, hoarse voice, difficulty swallowing.)
  • breathing (noisy breathing, cough, wheezing.)
  • circulation (clammy skin, feeling faint, sleepiness, confusion or collapse.)

Then you should use your adrenaline auto-injector (like an EpiPen) if you have one, and seek immediate medical help.

Most common causes of an allergic reaction 

The seven substances that most commonly cause allergic reactions are:

  • tree or grass pollen
  • insect stings
  • proteins from house dust mites
  • medicines
  • food such as peanuts, tree nuts, milk, eggs, fish and seafood

Symptoms of an allergic reaction 

Allergy symptoms vary from person to person and even with each reaction. But common, milder signs of an allergic reaction include:

  • irritation and swelling in your eyes, lips, tongue, mouth, throat and nose
  • sinus pain and runny nose
  • rash or hives
  • stomach irritation and pain
  • diarrhoea
  • coughing
  • wheezing
  • eczema flare-ups
  • nausea
  • vomiting

Signs of a severe allergic reaction 

It can be difficult to tell the difference between mild symptoms and more serious signs of anaphylaxis (or anaphylactic shock). If you’re in any doubt, seek immediate medical assistance.

Symptoms of anaphylaxis can include:

  • wheezing
  • tightness in your throat
  • coughing
  • hoarse voice
  • noisy breathing
  • trouble breathing
  • swollen lips, tongue, throat or face
  • skin flushing
  • skin turning pale, ashen or blue
  • dizziness
  • faintness
  • rapid heart rate
  • severe stomach pain
  • vomiting
  • diarrhoea
  • tiredness
  • confusion or agitation
  • uterine cramps in women
  • anxiety

And severe signs of anaphylaxis can include:

  • a dramatic fall in blood pressure
  • breathing difficulties
  • choking
  • wheezing
  • tongue or throat swelling
  • fainting or collapse
  • drowsiness
  • extreme confusion
  • cold skin
  • weak pulse
  • a child becoming floppy or finding it difficult to lift their head

When to seek medical attention 

If you or someone else is showing any of the signs listed above of anaphylactic shock, you should call 999, use an adrenaline auto-injector if you have one, and make sure the person having the allergic reaction is sitting or lying down.

Anaphylaxis can escalate very quickly, and you may not see the same symptoms each time you experience a reaction. If you are in any doubt seek urgent medical attention.

If your milder symptoms have started to become more extreme, unmanageable or have changed, make an appointment with your GP. You may want to go for blood or skin prick testing to confirm what substance you’re allergic to.

What can treat an allergic reaction? 

The best treatment for your allergic reaction depends on your symptoms. Some can be managed using antihistamine tablets, while others might need a direct solution like eye drops or a nasal spray. And if you have more severe reactions your doctor will prescribe an adrenaline auto-injector.

Most clinicians recommend second-generation antihistamines, as they don’t cause drowsiness. These include:

However, drowsy antihistamines like  promethazine (Phenergan), and chlorphenamine (Piriton) are all good treatments for skin symptoms.

Some symptoms can be managed more directly with nasal sprays like Dymista, which block triggers like pollen or dust mites while reducing inflammation in the nose.

Eye drops like Optrex tackle redness, itching and watery eyes. Or you can use corticosteroids  like Pirinase Allergy nasal spray or Beconase Hay Fever Relief spray to reduce swelling, redness and itching.

There are also allergy treatments suitable for children, like Cetirizine oral solution and Piriton Syrup.

If medication isn’t working, immunotherapy treatment for allergic reactions involves visiting a medical professional who will gradually and carefully expose you to your allergen, so your body becomes used to them. Your GP can refer you to a clinic.

9 tips for dealing with allergies 

Most allergies can be easily managed. Some simple steps to help you control your hay fever and allergy symptoms include:

  1. Avoiding the substance you’re allergic to.
  2. Keeping an allergy diary so you know what might be causing your symptoms.
  3. Carrying antihistamines like cetirizine, loratadine, or fexofenadine with you.
  4. Taking your treatments ahead of hay fever season to help manage symptoms before they get too severe.
  5. Planning to take 'safe' snacks or meals with you, and researching menus and food options ahead of time.
  6. Preventing cross-contamination by being careful how you store and prepare your food.
  7. Carrying two adrenaline auto-injectors if you're at risk of anaphylaxis.
  8. Avoiding areas you know might have allergens present, like a pet-owning friend’s house if you have a cat allergy.
  9. Considering wearing a medical bracelet or ID so people know what to do in an emergency.

Frequently asked questions about allergic reactions 

What are the nine most common allergies? 

The most common allergens in the UK are:

  • tree and grass pollen (hay fever or allergic rhinitis)
  • house dust mites
  • moulds (they can release spores into the air that you breathe in)
  • food (like peanuts, milk and eggs)
  • animal dander (tiny flakes or skin or hair)
  • insect stings
  • medication
  • latex (used to make some gloves and condoms)
  • household chemicals (including those in detergents and hair dyes)

Do allergies get worse with age? 

Most people grow out of childhood allergies, especially those who react to cow’s milk, eggs, wheat and soya. But some allergies develop for the first time in adulthood or worsen.

This can be due to:

  • your immune system changing and becoming less effective
  • prolonged exposure to your allergens
  • physical changes such as thinner skin allowing allergens to penetrate more easily
  • environmental factors such as climate change creating longer pollen seasons
  • medication interactions; allergic reactions can become more pronounced when combined with treatments such as blood pressure medications
  • your body’s stress response changing and increasing the release of histamines

Can you develop allergies while pregnant? 

Yes. When you’re pregnant, your hormones fluctuate, your immune system changes, and you experience increased blood flow. This can mean that your existing allergy symptoms can become more or less pronounced during pregnancy. Some people become sensitive to different or new allergens.

Sources 

Hanna Yusuf - Prescribing Pharmacist
Hanna Yusuf , Prescribing Pharmacist on 27 February 2026
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