Sodium Fluoride Toothpaste

What is high fluoride toothpaste?

High fluoride toothpaste is a prescription‑strength toothpaste that contains a higher level of fluoride than standard toothpaste.

It’s designed to give extra protection against tooth decay by helping to strengthen enamel and protect vulnerable areas of the teeth.

When should you use high fluoride toothpaste?

High fluoride toothpaste is recommended when your risk of tooth decay is higher than average. Examples of being at a higher risk include:

• frequently getting cavities
• having a dry mouth
• receding gums
• showing early signs of enamel damage
• wearing braces

Is sodium fluoride toothpaste the same as Duraphat?

Sodium fluoride toothpaste and Duraphat are not identical. However, Duraphat toothpaste is a type of sodium fluoride toothpaste.

Duraphat is available in two strengths: 2800ppm and 5000ppm fluoride, which are usually prescribed based on your individual level of tooth decay risk.

We currently only supply generic sodium fluoride toothpaste at 5000ppm.

How to use sodium fluoride toothpaste?

When using sodium fluoride toothpaste, you should brush your teeth three times instead of the usual two.

Always use this toothpaste as your dentist or pharmacist has instructed. When using sodium fluoride toothpaste:

• Apply a 2cm ribbon of toothpaste onto your toothbrush (roughly 3-5mg of fluoride).
• Brush your teeth vertically after each meal (from the gum to the top of the tooth).
• Spit out any excess foam/toothpaste, making sure not to swallow any.

Be careful and intentional while brushing. It should take about 2-3 minutes for you to properly brush your teeth.

Whether you’re confident you know how, or secretly a bit unsure, we’ve covered how to brush your teeth correctly, so you’ll always be getting the most out of your toothpaste.

How long should you use sodium fluoride toothpaste for?

 A dentist may recommend using 5000 ppm sodium fluoride toothpaste for as long as you’re considered at higher risk of tooth decay.

For some people, this may be a few months, while others may use it longer term to help keep decay under control. If your risk goes down, then you may be able to switch back to a standard toothpaste under guidance from your dentist.

If you’re ever unsure, speak to a pharmacist or dentist for more advice.

What if you miss a dose?

If you miss a brushing, you can carry on with your normal routine and just use the toothpaste at your next usual time.

Side effects of high fluoride toothpaste

As with any medication, using high fluoride toothpaste can cause unwanted side effects. They’re usually uncommon, mild, and go with time.

The main reported side effect is a slight burning sensation while using the toothpaste.

When to seek medical help

If you experience any of the following symptoms, it could be a sign of an allergic reaction. You should contact emergency services immediately if in the event of:

• swelling of the face and throat
• a skin rash
• breathing difficulties
• loss of consciousness

Do not drive yourself to a hospital. Instead get someone else to take you or wait for an ambulance.

When not to use sodium fluoride toothpaste

Sodium fluoride toothpaste is suitable for everyone. To make sure you’re safe to use this toothpaste, you should tell your dentist or pharmacist if:

• you have an intolerance to some sugars

You should not use this toothpaste if:

• you are allergic to sodium fluoride or any of the listed ingredients

When using this toothpaste, avoid fluoride tablets, drops, chewing gum, gels or varnishes.

Storage information

Store below 25°C in a cool, dry place out of sight and reach of children.

Do not use after the expiry date, referring to the last day of the month stated on the packaging. Once opened, use within 6 months.

What to do alongside your treatment

This type of toothpaste provides a high level of fluoride on its own, so additional fluoride products (such as fluoride mouthwashes) aren’t usually needed unless specifically advised by a dentist.

Alongside this, good everyday oral care still matters:

• brushing gently, or using a soft-bristled brush if you’ve got sensitive teeth
• limiting sugary or acidic snacks
• spit but don’t rinse, allowing the toothpaste to be a protective layer on your teeth

Frequently asked questions about sodium fluoride toothpaste

Is sodium fluoride toothpaste safe to use?

For most people, sodium fluoride toothpaste is considered safe when used as directed. Safety guidance mainly focuses on using the right amount for your age and avoiding swallowing toothpaste.

Is fluoride toothpaste bad for you?

Fluoride toothpaste isn’t bad for you when used as directed. It’s widely recommended by dentists because it helps strengthen teeth and reduce tooth decay.

How much fluoride is in toothpaste?

The average tube of toothpaste you can buy off the supermarket shelf usually contains between 1000-1450ppm fluoride, while prescription toothpaste contains a higher concentration of 2800ppm or 5000ppm.

Why did my dentist prescribe me sodium fluoride toothpaste?

A dentist may suggest or prescribe 5000 ppm sodium fluoride toothpaste if you’re considered at higher risk of tooth decay, as it gives teeth extra protection. This can include people who:

• get cavities more often
• have a dry mouth
• have receding gums/exposed roots
• show early signs of enamel damage

Sources

• Chapter 9: fluoride (2024). NHS England. [Accessed 23 April 2026]
• Sodium fluoride (2026). BNF. [Accessed 23 April 2026]