Top Seller

Colgate Duraphat Toothpaste

Based on 283 reviews

2800 & 5000ppm. Available in multiple pack sizes

  • High-fluoride toothpaste
  • Available in two strengths: 2800ppm and 5000ppm
  • Helps to prevent cavities and tooth decay
  • Prescription-only dental care product
Strength
Price

2800ppm - 1 Pack

£9.99

2800ppm - 2 Pack

£18.99

2800ppm - 3 Pack

£26.99

5000ppm - 1 Pack

£10.19

5000ppm - 2 Pack

£19.29

5000ppm - 3 Pack

£26.99
This treatment is inclusive of consultation & private prescription
How we are regulated
Alexandra Smith - Senior Medical Writer
Alexandra Smith
Senior Medical Writer
18/03/2026
17/03/2028
Ian Budd - Prescribing Pharmacist
Ian Budd
Prescribing Pharmacist
2037876

Buy Colgate Duraphat 5000ppm Toothpaste

You can buy Colgate Duraphat toothpaste as long as it's been approved and prescribed by one of our clinicians.

Available in two different strengths, 2800ppm or 5000ppm, Duraphat is a high-fluoride toothpaste designed to provide stronger protection for those at higher risk of cavities and tooth decay. It can be bought from Chemist4U in single, double and triple packs.

How does Duraphat Toothpaste work?

Duraphat contains high levels of sodium fluoride, helping to strengthen enamel and promote the remineralisation of the tooth surface, effectively preventing dental caries.

How to get Duraphat Toothpaste

It is only available with a prescription, so start your free consultation with Chemist4U today.

During your consultation, your clinician  will decide which strength of toothpaste will be right for you, depending on the current state of your teeth and how great your risk of tooth decay is.

What is Colgate Duraphat Toothpaste used for?

Consistent use of Colgate Duraphat Toothpaste can help you:

  • prevent tooth decay
  • reduce enamel erosion
  • repair and strengthen your teeth
  • ease a dry mouth
  • avoid cavities if you wear braces and other orthodontic appliances

How to use Colgate Duraphat Toothpaste

How you use Duraphat depends on the strength you’ve been prescribed:

How to use Duraphat 5000ppm

You should use Duraphat 5000ppm three times a day, 30 minutes after each meal

  1. 1. Apply a 2cm strip of toothpaste on your brush.
  2. 2. Brush vertically, from the gum to the tip of your tooth.
  3. 3. Careful brushing should take around three minutes.
  4. 4. Spit out any excess foam, and do not swallow.

Avoid drinking or rinsing out your mouth for 30 minutes after brushing. 

How to use Duraphat 2800ppm

You should use Duraphat 2800ppm twice a day.  

  1. 1. Apply a 1cm strip of toothpaste on your brush.
  2. 2. Brush your teeth for one minute.
  3. 3. Spit out any excess foam, and do not swallow.

Avoid drinking or rinsing out your mouth for 30 minutes after brushing.

How long should you use Duraphat Toothpaste for?

There’s no set treatment period for Duraphat Toothpaste, though most people start with a three month prescription.

You should use it as long as your dentist or prescribing pharmacist recommends.

We sell Duraphat Toothpaste in one, two and three packs, meaning you can save money if you intend to use the treatment long-term.

What to do if you miss a dose

If you forget to use your Duraphat Toothpaste, simply brush your teeth as soon as your remember. However, don’t use more than a 2cm strip of toothpaste.

Duraphat Toothpaste side effects

As with any prescription medication, you may experience some side effects when using Duraphat Toothpaste.

Rare side effects (experienced by less than one in 1,000 people) include rashes, itching, swelling and redness.

For more information, please read the patient information leaflet. If you encounter any side effects not listed in the patient information leaflet, you can report them to the MHRA Yellow Card Scheme.

Who can use Duraphat Toothpaste

Duraphat 2800ppm toothpaste can be used by children aged 10 and over, whereas Duraphat 5000ppm can only be used in people over 16.

At Chemist4U we do not prescribe Duraphat Toothpaste to anyone under 18 years old.  

Do not use Duraphat Toothpaste if you are allergic to sodium fluoride, or any of the other ingredients in the product.

Since Duraphat is already high in fluoride, avoid taking additional fluoride tablets, drops, chewing gums, gels or varnishes when using the toothpaste. Similarly, avoid fluoridated water and salt.

How to store your treatment

Keep your Duraphat Toothpaste out of the reach of children, and below 25°C.

Do not use your treatment after the expiry date stated on the tube and carton.

 

Find similar products

Frequently asked questions about Duraphat Toothpaste 5000ppm

Why do dentists prescribe Duraphat Toothpaste?

Dentists prescribe Duraphat Toothpaste to patients who have a higher risk of tooth decay, or a history of cavities. However, it can also be prescribed for other reasons, such as treating dry mouth.

Does Duraphat help receding gums?

Duraphat does not treat or prevent gum recession. However, its high fluoride can reduce sensitivity and improve enamel protection, which may help manage symptoms associated with receding gums. Good oral hygiene in general can help prevent gum recession.

Does Duraphat make teeth whiter?

No, Colgate Duraphat Toothpaste isn’t specifically designed to make your teeth whiter. However, regular use may help protect the natural whiteness of your teeth.

Does Duraphat rebuild enamel?

Yes, Duraphat Toothpaste can help remineralise and strengthen enamel, helping you avoid tooth decay in the process.

Will Duraphat get rid of my toothache?

You shouldn’t rely on Duraphat to get rid of a toothache. Although it may be able to help repair and strength your teeth, you should always go to a dentist if you’re in pain.

Colgate Duraphat Toothpaste Reviews

white-star white-star white-star white-star white-star
By Daniel Tuck,
August 18, 2026
Made my teeth much stronger
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By Sue,
August 18, 2026
Very good recommended by my dentist for extra protection of fluoride for my brittle teeth.
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By Katie Coe,
August 18, 2026
This product protects your teeth well and really works for reducing sensitivity
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By Amanda Dooris,
August 18, 2026
It really helps with oral hygiene and is really good helping with sensitivity.
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By Donna from bradford,
August 18, 2026
Great taste seems to help with my bleeding gums (not much anymore) hygenist happy

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