Available in two different strengths, 2800ppm or 5000ppm, Duraphat is a high-fluoride toothpaste designed to provide stronger protection for those at higher risk of cavities and tooth decay. It can be bought from Chemist4U in single, double and triple packs.

How does Duraphat Toothpaste work?

Duraphat contains high levels of sodium fluoride, helping to strengthen enamel and promote the remineralisation of the tooth surface, effectively preventing dental caries.

How to get Duraphat Toothpaste

It is only available with a prescription, so start your free consultation with Chemist4U today.

During your consultation, your clinician will decide which strength of toothpaste will be right for you, depending on the current state of your teeth and how great your risk of tooth decay is.

What is Colgate Duraphat Toothpaste used for?

Consistent use of Colgate Duraphat Toothpaste can help you:

prevent tooth decay
reduce enamel erosion
repair and strengthen your teeth
ease a dry mouth
avoid cavities if you wear braces and other orthodontic appliances

How to use Colgate Duraphat Toothpaste

How you use Duraphat depends on the strength you’ve been prescribed:

How to use Duraphat 5000ppm

You should use Duraphat 5000ppm

Brush vertically, from the gum to the tip of your tooth.
Careful brushing should take around three minutes.
Spit out any excess foam, and do not swallow.

Avoid drinking or rinsing out your mouth for 30 minutes after brushing.

How to use Duraphat 2800ppm

You should use Duraphat 2800ppm twice a day.

Apply a 1cm strip of toothpaste on your brush.
Brush your teeth for one minute.
Spit out any excess foam, and do not swallow.

Avoid drinking or rinsing out your mouth for 30 minutes after brushing.

How long should you use Duraphat Toothpaste for?

There’s no set treatment period for Duraphat Toothpaste, though most people start with a three month prescription.

You should use it as long as your dentist or prescribing pharmacist recommends.

We sell Duraphat Toothpaste in one, two and three packs, meaning you can save money if you intend to use the treatment long-term.

What to do if you miss a dose

If you forget to use your Duraphat Toothpaste, simply brush your teeth as soon as your remember. However, don’t use more than a 2cm strip of toothpaste.

Duraphat Toothpaste side effects

As with any prescription medication, you may experience some side effects when using Duraphat Toothpaste.

Rare side effects (experienced by less than one in 1,000 people) include rashes, itching, swelling and redness.

For more information, please read the patient information leaflet. If you encounter any side effects not listed in the patient information leaflet, you can report them to the MHRA Yellow Card Scheme.

Who can use Duraphat Toothpaste

Duraphat 2800ppm toothpaste can be used by children aged 10 and over, whereas Duraphat 5000ppm can only be used in people over 16.

At Chemist4U we do not prescribe Duraphat Toothpaste to anyone under 18 years old.

Do not use Duraphat Toothpaste if you are allergic to sodium fluoride, or any of the other ingredients in the product.

Since Duraphat is already high in fluoride, avoid taking additional fluoride tablets, drops, chewing gums, gels or varnishes when using the toothpaste. Similarly, avoid fluoridated water and salt.

How to store your treatment

Keep your Duraphat Toothpaste out of the reach of children, and below 25°C.

Do not use your treatment after the expiry date stated on the tube and carton.

Information

Ingredients

1g of toothpaste contains 5mg fluoride (as sodium fluoride), corresponding to 5000ppm fluoride OR 2.8mg fluoride, corresponding to 2800ppm.

Also contains: liquid sorbitol (non-crystallising), dental type silica, dental type silica (precipitated), macrogol 600, tetrapotassium pyrophosphate, xanthan gum, sodium benzoate (E211), sodium laurilsulfate, spearmint flavouring (containing peppermint oil, carvone, spearmint oil, menthol, anethol, and lemon oil), saccharin sodium, Brilliant Blue FCF (E133) and purified water.

Drug Data

Leaflet

View product information leaflet

Administration Method

Topical

Drug Class

Caries prophylactic agent

Product Type

GSL

Strength

5000ppm

Dosage Form

Toothpaste

Dose Information

Use a 2cm ribbon of toothpaste / 3 times a day.

Maximum Intake

Use a 2cm ribbon of toothpaste / 3 times a day.

Brand Information

Brand Name

Colgate

Brand Address

Lloyd St N, Williams House , Greater Manchester, Manchester M15 6SE

Questions

Ask a Pharmacist

Got a question for one of our pharmacists?

Visit Help Centre

Need a hand?

Our pharmacy team are on hand to answer any questions or concerns you might have.

T: 01695 474433 Get in touch

Delivery

Shipping Times

Method	Handling Time	Transit Time	Timescale	Approx Cost
Delivery in 1-2 working days (Free on orders over £39)	1	1	2	£3.95
Next Day Guaranteed (1 Working Day)	0	1	1	£6.95
Next Day (Royal Mail Special Delivery)	0	1	1	£8.95

Times are given in working days and are approximate. Costs may change based on order total, day of the week or location within the UK. Ability to hit timescales will depend on whether the products are ordered before a cut off time, as well as additional administration time incurred in reviewing your order.

Please review the estimates at the checkout.

Shipping Costs

Free UK Delivery on all orders over £39 * - Delivery within 1-2 working days.

Standard UK Delivery - £3.95* - Delivery within 1-2 working days.

Temperature Controlled Delivery - £0.00 (Free) - Delivery within 1-3 working days.

Please Note: These prices are shown as a guide only. All delivery times are approximate but have been obtained in good faith.

*Excluding refrigerated products and treatments which are subject to different postage charges.

Discreet Delivery

All our items are sent completely discreet for your peace of mind.

This means the packaging is plain, there is no mention of what product is inside your package and there is no mention of Chemist4U either.

We respect that many of our products are of a sensitive nature - this is why we take every step to keep your purchases private.

Returns Information

Customers can read our full returns policy by clicking here

Find similar products

Dental Care Treatments

Colgate Duraphat Toothpaste Reviews

By Malcolm Ramsden-Frankland,

March 17, 2026

It is effective in maintaining good tooth and gum health.

By Sarah and Guy ,

March 17, 2026

This stuff works for sensitive teeth. Recommended by my dentist, makes a big difference.

By Nicola,

March 10, 2026

So far so good. Seems to be alleviating the symptoms of sensitivity for my receding gums.

By Guy F,

March 03, 2026

Great service and quick delivery

By A T Senior,

March 03, 2026

Exceptional service and delivery

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Frequently asked questions about Duraphat Toothpaste 5000ppm

Why do dentists prescribe Duraphat Toothpaste?

Dentists prescribe Duraphat Toothpaste to patients who have a higher risk of tooth decay, or a history of cavities. However, it can also be prescribed for other reasons, such as treating dry mouth.

Does Duraphat help receding gums?

Duraphat does not treat or prevent gum recession. However, its high fluoride can reduce sensitivity and improve enamel protection, which may help manage symptoms associated with receding gums. Good oral hygiene in general can help prevent gum recession.

Does Duraphat make teeth whiter?

No, Colgate Duraphat Toothpaste isn’t specifically designed to make your teeth whiter. However, regular use may help protect the natural whiteness of your teeth.

Does Duraphat rebuild enamel?

Yes, Duraphat Toothpaste can help remineralise and strengthen enamel, helping you avoid tooth decay in the process.

Will Duraphat get rid of my toothache?

You shouldn’t rely on Duraphat to get rid of a toothache. Although it may be able to help repair and strength your teeth, you should always go to a dentist if you’re in pain.

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