Top Seller

Colgate Duraphat Toothpaste

Based on 151 reviews

2800 & 5000ppm. Available in multiple pack sizes

  • High-fluoride toothpaste
  • Helps to prevent cavities and tooth decay
  • Prescription-only dental care product
Strength
Price

2800ppm - 1 Pack

£11.99

2800ppm - 2 Pack

£20.99

2800ppm - 3 Pack

£28.99

5000ppm - 1 Pack

£11.29

5000ppm - 2 Pack

£21.59

5000ppm - 3 Pack

£31.79
This treatment is inclusive of consultation & private prescription
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How we are regulated
Alexandra Smith - Senior Medical Writer
Alexandra Smith
Senior Medical Writer
18/11/2025
17/11/2027
Ayesha Bashir - Prescribing Pharmacist
Ayesha Bashir
Prescribing Pharmacist
2209645

Buy Colgate Duraphat Toothpaste 

You can buy Colgate Duraphat toothpaste as long as it's been approved and prescribed by one of our clinicians.  

Available in two different strengths, 2800ppm or 5000ppm, Duraphat is a high-fluoride toothpaste designed to provide stronger protection for those at higher risk of cavities and tooth decay. It can be bought from Chemist4U in single, double and triple packs. 

Duraphat contains high levels of sodium fluoride, helping to strengthen enamel and promote the remineralisation of the tooth surface, effectively preventing dental caries.  

It is only available with a prescription, so start your free consultation with Chemist4U today. 

During your consultation, your doctor will decide which strength of toothpaste will be right for you, depending on the current state of your teeth and how great your risk of tooth decay is. 

Benefits of Colgate Duraphat Toothpaste 

Consistent use of Colgate Duraphat Toothpaste can help you: 

  • prevent tooth decay 
  • reduce enamel erosion 
  • repair and strengthen your teeth 
  • ease a dry mouth 
  • avoid cavities if you wear braces and other orthodontic appliances 

How to use Colgate Duraphat Toothpaste 

You should use Colgate Duraphat Toothpaste 3 times a day, after each meal:  

  1. 1. Apply a 2cm strip of toothpaste on your brush. 
  2. 2. Brush vertically, from the gum to the tip of your tooth. 
  3. 3. Spit out any excess foam, and do not swallow. 

How long should you use Duraphat Toothpaste for? 

There’s no set treatment period for Duraphat Toothpaste, though most people start with a 3-month prescription. 

You should use it as long as your dentist or prescribing pharmacist recommends. 

Duraphat Toothpaste side effects 

As with any prescription medication, you may experience some side effects when using Duraphat Toothpaste. Rare side effects (experienced by less than 1 in 1,000 people) include rashes, itching, swelling and redness.  

For more information, please read the patient information leaflet. If you encounter any side effects not listed in the patient information leaflet, you can report them to the MHRA Yellow Card Scheme. 

When to avoid Duraphat Toothpaste

Duraphat 2800ppm toothpaste can be used by children aged 10 and over, whereas the 5000ppm strength can only be used in people over 16. 

Do not use Duraphat Toothpaste if you are allergic to sodium fluoride, or any of the other ingredients in the product.  

Since Duraphat is already high in fluoride, avoid taking additional fluoride tablets, drops, chewing gums, gels or varnishes when using the toothpaste. Similarly, avoid fluoridated water and salt.  

Find similar products

Colgate Duraphat Toothpaste Reviews

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By Daisy,
December 02, 2025
Does exactly what it is intended for, Dentist recommended for twice daily application.
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By H Bowes,
December 02, 2025
Suggested by my dentist, much cheaper online.
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By John Warrington ,
December 02, 2025
Easy to order and fast delivery
white-star white-star white-star white-star white-star
By Duncan Rogers,
November 25, 2025
My dentist recommends this product and I still have most of my teeth. (Missing teeth unrelated to products use)
white-star white-star white-star white-star white-star
By Sharon Davies,
November 25, 2025
Good if you suffer with tooth and gum problems

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Frequently Asked Questions

Why do dentists prescribe Duraphat Toothpaste?

Dentists prescribe Duraphat Toothpaste to patients who have a higher risk of tooth decay, or a history of cavities. However, it can also be prescribed for other reasons, such as treating dry mouth.

Does Duraphat help receding gums?

Yes, Duraphat can help prevent receding gums, while stopping any existing issues from getting worse.

Does Duraphat make teeth whiter?

No, Colgate Duraphat Toothpaste isn’t specifically designed to make your teeth whiter. However, regular use may help protect the natural whiteness of your teeth.

Does Duraphat rebuild enamel?

Yes, Duraphat Toothpaste can help remineralise and strengthen enamel, helping you avoid tooth decay in the process.
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