Nytol Original 25mg - 20 Caplets

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The Product Information was written and researched on 16/11/2020 . Find out more. See less.

What are Nytol Original Tablets?

Nytol Original is a specially formulated remedy for short-term sleeplessness and stress. It has been shown to help sufferers of insomnia fall asleep faster, have a longer and deeper sleep, and to wake up feeling rested in the morning.


What is insomnia?

Insomnia is a sleep disorder which can stop you from getting a full night’s sleep. Everyone has the occasional sleepless night, but if you find that you regularly struggle to fall or stay asleep you could be suffering from insomnia. When you don’t get enough sleep, you can find it more difficult to concentrate and may feel tired and irritable, which is why many people who suffer from insomnia reach for short-term remedies like Nytol.


How will this product help to treat my insomnia?

Nytol Original contains diphenhydramine hydrochloride, which works by blocking the production of histamine in your body. Histamine stimulates arousal-promoting areas of your brain, so blocking this process helps to encourage the first drowsy stage of sleep and reduce your levels of awareness. This will help you to drift off into a restful night’s sleep.


When should I take Nytol?

If you’ve been suffering through sleepless nights and are looking for a temporary solution which could help you to get some sleep, Nytol Original could be the right product for you. It can help you to get some much-needed rest, perfect for those who are suffering from stress from work or just everyday life. You should take these tablets around 20 minutes before bedtime, making sure you have enough time to get the full night’s sleep this product can provide.


Can I take this product if I’m pregnant or breastfeeding?

If you are pregnant or breastfeeding, you should speak to your doctor or Chemist 4 U pharmacist before taking this product. Some medications may not be safe for you and your baby at this time, and a medical professional can suggest an alternative product if they think you will need it.


Can I take these tablets if I am taking other medication?

You should speak to your doctor or Chemist 4 U pharmacist before taking Nytol if you are taking any other medication, including those you purchased without a prescription. Some medications can interact when taken together, making them less effective or causing unwanted side effects. Speak to your doctor before using this product if you are taking:

  • Tricyclic antidepressants
  • Monoamine Oxidase Inhibitors (MAOIs) which are prescribed for depression, e.g. Isocarboxazid, Phenelzine, Selegiline, Tranylcypromine
  • Atropine used to dilate the pupils of the eyes
  • Other medicines which make you drowsy
  • Other antihistamines, including those used on the skin and those in cough and cold medicines


Can I drive after taking Nytol Original?

As Nytol Original is designed to make you feel sleepy or drowsy, you should not drive or operate tools or machinery after you have taken this medicine.


Can I drink alcohol while I’m taking this product?

You should not drink alcohol while using Nytol Original, as it can make the sedative effect of this product more pronounced and difficult to manage.


How to take Nytol Original Tablets

Swallow 2 Nytol Original Tablets with water, 20 minutes before you plan to go to bed. As this product is designed to help you get a full night’s sleep, it is recommended that you take these tablets at least 7 or 8 hours before you need to wake up. This product may become less effective if you use it continuously, speak to your doctor or Chemist 4 U pharmacist if your symptoms do not improve and do not take these tablets for more than 2 weeks.


Do I need a prescription for Nytol Original sleeping tablets?

You do not need a prescription for Nytol Original, however, you will be asked to complete a short medical questionnaire by your Chemist 4 U pharmacist before we can take your order. This includes some simple questions that all pharmacies legally are required to ask before supplying this kind of product. This helps our pharmacy team to be sure that this product is the best choice for you.


When should Nytol Original not be used?

Nytol Original should not be taken by anyone under the age of 16 or elderly people who suffer from confusion. Do not use this product if you are allergic to diphenhydramine hydrochloride or any of the other listed ingredients. If you have an obstruction in your stomach or gut (such a one created by an ulcer), do not take Nytol Original. Speak to your doctor or Chemist 4 U pharmacist before taking this product if you:

  • Have asthma, bronchitis, or Chronic Obstructive Pulmonary Disease (COPD)
  • Have narrow-angle glaucoma (a form of raised pressure in the eye)
  • Have an enlarged prostate or urinary retention
  • Have moderate to severe liver or kidney disease
  • Have myasthenia gravis, epilepsy, or seizure disorders
  • Have persistent sleeping difficulties


Does this product have any side effects?

Nytol Original, like all medicines, can have side effects but not everyone gets them. These include:

  • Drowsiness
  • Tiredness
  • Reduced attention
  • Unsteadiness
  • Dry mouth
  • Dizziness
  • Symptoms of an allergic reaction (e.g. rash, shortness of breath, swelling), blurred vision, palpitation, irregular heartbeat
  • Muscle twitching, convulsions, headache, pins and needles
  • Nausea, vomiting, thicker bronchial mucus, difficulty passing urine.

If you experience these or any other symptoms while taking this product, stop use and contact your doctor or Chemist 4 U pharmacist right away. For more information about reporting side effects of medication, please see the MHRA’s Yellow Card Scheme.


How to store these tablets

Store Nytol Original in a cool, dry place. Store in original packaging and do not use once expiry date printed on the packaging has passed. Keep out of sight and reach of children.


Important Information

This product is a medicine; make sure to speak to your doctor or Chemist 4 U pharmacist before taking this product if you have an underlying medical problem or are taking any other medicine or complementary therapy. If your symptoms get worse or continue after taking this product, contact us or your doctor. For medical services in your area, please refer to https://www.nhs.uk

If you are pregnant, trying to become pregnant, or breastfeeding, speak to your doctor or our pharmacist before taking this product. If you suffer from any allergies, ask your doctor or our pharmacist if this medicine is right for you.

Store all medicines out of sight and reach of children.

Please read the included leaflet carefully before using this product.

Please contact your GP if appropriate regarding this product.


Helpful Advice on Medication Restrictions & Addiction

For further information on our medication restrictions policy, please click here.

If you are concerned about addiction of 'over the counter' medication we urge you to visit the below links for professional help and advice:

Active Ingredients

  • Diphenhydramine


  • Each tablet contains Diphenhydramine Hydrochloride 25 mg

    Other ingredients: Anhydrous lactose, microcrystalline cellulose, maize starch, stearic acid and silicon dioxide

Product Data

Days Supply
Active Ingredient(s)
20 Tablets

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