Evorel Conti Patches

Buy Evorel Conti Patches 

Evorel Conti Patches is a hormone replacement therapy (HRT) that contains two types of female hormones: oestrogen and progestogen. They are used in postmenopausal women with at least 18 months since their last natural period.

The hormones are spread evenly in each patch, slowly passing into your body through the skin, helping to alleviate the symptoms after menopause.

Each pack contains 8 patches.

How Evorel Conti Patches work

Evorel Conti Patches are known as continuous combined HRT. The hormones in the patch are released continuously. 

It contains the hormones estradiol (oestrogen) and norethisterone acetate (progestogen).

The patches replace the oestrogen normally released by the ovaries. In women who still have a womb, using an oestrogen hormone regularly may cause the womb lining to build up and become thicker, making it necessary to add a progestogen hormone. 

Progestogen helps to shed the lining of the womb, preventing any problems. 

Directions

Always use Evorel Conti Patches exactly as described in the patient information leaflet or as your doctor / Chemist4U pharmacist has told you. 

Do not use a patch if its protective pouch is open. Using the notches as a guide, tear along the 2 edges of the pouch. With the protective backing facing you, bend and peel off half of the backing. Don’t touch the sticky side; it may not stick properly if you do. 

Place the patch on a hairless area of skin below the waist. Do not apply the patch to the same area of skin twice in a row or on top of cuts, spots, or irritated skin.

Do not put it on or near the breasts.

Do not use creams, moisturisers or talcum powder on the skin before applying the patch.

Do not wear the patch under elasticated areas or a tight waistband. 

Apply the open half of the patch to the skin. Remove the remaining backing and press down the rest of the patch. Warm and press the patch down to the skin with the palm of the hand for approximately 30 seconds. Pressure and heat by the hand are crucial to achieving maximum adhesion of the patch. 

To remove the patch, peel the edge smoothly away from the skin. Fold the patch in half so that the sticky side sticks to itself. 

If your patch falls off, apply a new patch, but keep to your original ‘patch change’ days. If you have just had a bath or shower, wait until your skin cools before you apply a new patch.

You must change your patches twice a week to give your body a steady supply of hormones. Change your patch on the same two days every week. This means one patch is on for three days and the other for four.

When you can start using Evorel Conti Patches 

You can put a patch on at the end of a treatment cycle or 2 weeks after you finish using another HRT product if you are changing from a HRT medicine that gives you a withdrawal bleed. 

If you are using another type of HRT, the day you can start using Evorel Conti Patches will depend on that type of HRT. You should talk to your healthcare provider for advice on when you can start using the patches.

If you have not been using another type of HRT, you can put on a patch anytime.

Side effects

Like all medicines, Evorel Conti Patches may cause side effects in some people, but these won’t affect everybody. Common side effects may include: 

• Irritated, itchy, red skin and rash where the patch is applied
• Feeling depressed, nervous or anxious 
• Being unable to sleep
• Headaches
• Heart palpitations 
• Varicose veins 
• Flushing and skin reddening
• Breast pain 
• Numb or tingling hands or feet
• Nausea 
• Diarrhoea 
• Stomach ache 
• Pain in the back or joints 
• Painful periods or thick white discharge from the vagina 
• Discharge from the vagina 
• Irregular, heavy or prolonged bleeding from the vagina, including after sex
• Water retention or build-up of fluid under the skin (oedema)
• Feeling tired
• Weight gain

For more information on potential side effects, refer to the patient information leaflet. If you experience any side effects, including any not included in the patient information leaflet, you can report them using the MHRA Yellow Card Scheme.

Serious side effects

Seek emergency medical attention if you notice any signs of a severe allergic reaction, symptoms of which include swelling of the face and throat, skin rash, breathing difficulties and/or loss of consciousness. 

Immediately remove the patch and seek medical advice immediately if you notice any of the following:

• Yellowing of the skin or the whites of your eyes (jaundice). These may be signs of liver disease
• A swollen face, tongue, throat, difficulty swallowing, hives and difficulty breathing. These may be signs of angioedema
• A significant rise in your blood pressure (symptoms include a headache, tiredness and dizziness
• Migraine-like headaches which happen for the first time 
• Painful swelling and redness of the legs, sudden chest pain and difficulty breathing (symptoms of a blood clot in the leg or lungs)
• Pain in your chest that spreads to your arm and neck (signs of a heart attack)
• You notice changes in your breasts e.g. dimpling of the skin, changes in the nipple or any lumps

Warnings

Evorel Conti Patches may be unsuitable for certain people. Do not use these patches if you are allergic to any of the ingredients or if:

• You have or have ever had breast cancer, or you are suspected of having it 
• You have cancer which is sensitive to oestrogens, such as cancer of the womb lining (endometrium), or you are suspected of having it 
• You have unexplained vaginal bleeding 
• You have excessive thickening of the womb lining (endometrial hyperplasia) that is not being treated 
• You have or have ever had a blood clot in the legs (thrombosis) or lungs (pulmonary embolism) 
• You have a blood clotting disorder such as protein S, protein C or antithrombin deficiency 
• You have or have recently had a disease caused by blood clots in the arteries e.g. heart attack, stroke or angina
• You have ever had liver disease, and your liver function tests have not returned to normal 
• You have porphyria 

Talk to your doctor or Chemist4U pharmacist before using this medicine if: 

• You have ever had fibroids inside your womb 
• You have endometriosis or endometrial hyperplasia 
• You are at an increased risk of developing blood clots
• You are at an increased risk of getting oestrogen-sensitive cancer (you have a close relative who has had this type of cancer)
• You have high blood pressure 
• You have a liver disorder e.g. a benign tumour 
• You have diabetes 
• You have gallstones 
• You suffer from migraines or severe headaches 
• You have systemic lupus erythematosus (SLE)
• You have epilepsy 
• You have asthma 
• You are due to have surgery
• You have a disease affecting the eardrum and hearing (otosclerosis) 
• You have very high levels of fat in your blood (triglycerides)
• You have fluid retention due to cardiac or kidney problems 
• You have hereditary and acquired angioedema 

Women over the age of 60 who use oestrogen-progestogen HRT are slightly more likely to develop heart disease than those who are not using it. 

The risk of having a stroke is higher in HRT users than non-users. The risk of a stroke due to HRT increases slightly with age.

The risk of blood clots in the vein is about 1.3 to 3 times higher in HRT users than non-users, especially during the first year of using it. Blood clots can be serious, and if not treated, they can be fatal. 

Using combined oestrogen-progestogen HRT slightly increases the risk of breast cancer. The risk depends on how long you use HRT and becomes apparent within 3 years of use. After stopping HRT, the extra risk will decrease over time; however, if you have used HRT for more than 5 years, the risk may persist for 10 years or more.

The use of oestrogen-progestogen HRT has been associated with a slightly higher risk of ovarian cancer. The risk varies with age. 

Women who start using Evorel Conti Patches and other similar medicines after the age of 65 may have a slight increase in the risk of dementia.

Using/taking other medicines

If you are taking or have recently taken any medication, including medication obtained without a prescription, talk to your healthcare provider before using this product.

You must tell your healthcare provider if you are taking the following medicines:

• Medicines to help you sleep (barbiturates) 
• Phenylbutazone, which is used for pain and inflammation
• Metoprobamate, which is used for anxiety 
• Medication for epilepsy e.g. phenobarbital, phenytoin or carbamazepine 
• Medicines for tuberculosis e.g. rifampicin or rifabutin 
• Medications used to treat HIV infection e.g. nevirapine, efavirenz, ritonavir and nelfanavir 
• The herbal remedy St John’s wort
• Medication for hepatitis C infection e.g. telaprevir 
• Bosentan, which is used for high blood pressure in the blood vessels of the lungs 

Pregnancy and breastfeeding

This product is for postmenopausal women only. If you become pregnant,  contact your healthcare provider immediately and remove the patch. If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, you must ask your doctor or Chemist4U pharmacist for advice before using any new medicine. 

Storage information

Store in a cool, dry place out of sight and reach of children. Do not use after the expiry date, referring to the last day of the month stated on the packaging. Do not throw away any medicines via wastewater or household waste.

Important information

This product is a medicine; make sure to speak to your doctor or Chemist4U pharmacist before using this product if you have an underlying medical problem or are taking any other medicine or complementary therapy. If your symptoms get worse or continue after using this product, contact us or your doctor. For medical services in your area, please refer to https://www.nhs.uk

If you are pregnant, trying to become pregnant, or breastfeeding, speak to your doctor or Chemist4U pharmacist before using this product. If you suffer from any allergies, ask your doctor or Chemist4U pharmacist if this medicine is right for you.

Store all medicines out of sight and reach of children.

Please read the included leaflet carefully before using this product.

Please contact your GP if appropriate regarding this product.