Duac Once Daily Gel

Based on 7 reviews

Available in 3% and 5%. Multiple size packs available

  • Topical treatment for mild to moderate acne
  • Contains clindamycin and benzoyl peroxide
  • Always read the patient information leaflet before use. 
Upon completion of a medical consultation with one of our health care professionals you can expect prices to start from £20.79
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Prescription Included
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Treatment Included
All inclusive price starts from £20.79
This treatment is inclusive of consultation & private prescription
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Faye Bonnell - Medical Content Writer
Faye Bonnell
Medical Content Writer
13/11/2024
12/11/2026
James O'Loan - CEO & Superintendent Pharmacist
James O'Loan
CEO & Superintendent Pharmacist
2084549
13/11/2024

Buy Duac Once Daily Gel

Duac Once Daily Gel is a topical medication that treats acne by reducing whiteheads and blackheads and preventing the growth of bacteria. 

It is suitable for those with mild to moderate acne. 

 

How Duac Once Daily Gel works

Duac Once Daily Gel contains two active ingredients: clindamycin and benzoyl peroxide. 

Clindamycin is a topical antibiotic that kills the bacteria trapped in the pores that cause acne. 

Benzoyl peroxide helps break down the top layer of skin, increasing cell turnover and shedding dead skin cells that block the pores.

 

Directions

Always use Duac Once Daily Gel exactly as described in the patient information leaflet or as your doctor / Chemist4U pharmacist has told you. 

This product should be used once a day in the evening. 

Completely remove makeup and wash the affected area of skin. Rinse your skin with warm water and gently pat dry. Apply a thin layer of gel onto the affected area, then gently massage it into the skin using your fingertips.

Use a fingertip-sized amount if you’re using it only on your face. 

Don’t apply too much or exceed the recommended dosage; this will not help your acne clear up quicker and may cause some skin irritation.

It could take around 2-5 weeks to see a noticeable improvement in your acne. You shouldn’t use Duac for more than 12 weeks at a time. Always follow your doctor or Chemist4U pharmacist’s advice on how long your treatment should last.

 

Side effects

Like all medicines, Duac Once Daily Gel may cause side effects in some people, but these won’t affect everybody. Common side effects of this product may include:

 

  • Skin burning sensation 
  • Peeling skin 
  • Itchy skin 
  • Dry skin
  • Redness of the skin 

 

If you experience any side effects, including any not included in the patient information leaflet, you can report them using the MHRA Yellow Card Scheme.

 

Serious side effects

Seek emergency medical attention if you notice any signs of a severe allergic reaction, symptoms of which include swelling of the face and throat, skin rash, breathing difficulties and/or loss of consciousness. 

If you experience any of the following side effects, stop using this product immediately and seek medical advice straight away:

 

  • Severe burning, peeling or itching 
  • Severe or prolonged diarrhoea or abdominal cramps

 

Warnings

Duac Once Daily Gel may be unsuitable for certain people. Do not use this product if you are allergic to any of the ingredients.

Talk to your doctor or Chemist4U pharmacist before using this medicine if: 

 

  • You have regional enteritis
  • You have ulcerative colitis 
  • You have antibiotic-associated colitis  

 

Do not let this product come into contact with coloured fabrics, as it may cause bleaching.

Duac Once Daily Gel can make your skin more sensitive to the sun. Therefore, while using this product, wear sun cream and cover-up.

Keep this product away from your mouth, lips, eyes and inside your nose.

You must tell your healthcare provider if you are using soaps or cosmetics with drying effects or products with large amounts of alcohol.

 

Using/taking other medicines

If you are taking or have recently taken any medication, including medication obtained without a prescription, talk to your GP or pharmacist before using this product.

This product can affect general anaesthesia.

You must tell your healthcare provider if you are taking or using any of the following medications:

 

  • Medicines containing erythromycin 
  • Acne medicines, including tretinoin, isotretinoin or tazarotene
  • Dapsone 
  • Sulfacetamide 
  • Other acne treatments, including antibiotics 
  • Medicated abrasive soaps and cleansers

 

Age restrictions 

Unfortunately, we cannot prescribe this product from our clinic to anyone under 18 years old.

 

Pregnancy and breastfeeding

Do not apply this product to your breasts if you are breastfeeding. If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, you must ask your doctor or Chemist4U pharmacist for advice before using any new medicine. 

 

Storage information

Store below 25°C in a cool, dry place out of sight and reach of children. Do not use after the expiry date, referring to the last day of the month stated on the packaging. Do not throw away any medicines via wastewater or household waste.

 

Important information

This product is a medicine; make sure to speak to your doctor or Chemist4U pharmacist before using this product if you have an underlying medical problem or are taking any other medicine or complementary therapy. If your symptoms get worse or continue after using this product, contact us or your doctor. For medical services in your area, please refer to the NHS website. 

If you are pregnant, trying to become pregnant, or breastfeeding, speak to your doctor or Chemist4U pharmacist before using this product. If you suffer from any allergies, ask your doctor or Chemist4U pharmacist if this medicine is right for you.

Store all medicines out of sight and reach of children.

Please read the included leaflet carefully before using this product.

Please contact your GP if appropriate regarding this product.

Find similar products

Duac Once Daily Gel Reviews

white-star white-star white-star white-star white-star
By Natalie,
July 23, 2025
Already seeing results
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By Menzies Norwich,
July 22, 2025
white-star white-star white-star white-star white-star
By Hermina ,
November 19, 2024
Very good and works for all types of skin
white-star white-star white-star white-star white-star
By Customer from Kent,
July 30, 2024
Excellent for acne
white-star white-star white-star white-star white-star
By Natasha,
November 16, 2021
10

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Frequently Asked Questions

What causes acne?

Acne can be caused by a variety of reasons, but the most common cause is a change in hormone levels.

This is why acne is most common in teenagers, during pregnancy, and at different times during your menstrual cycle.

Hormonal changes can cause the glands next to hair follicles to produce more oil (sebum) than normal, which can change the activity of a normally harmless bacterium to become aggressive and cause inflammation and pus.

Acne can cause different types of spots to develop on the face, back and chest including:

  • Blackheads: bumps that are small and black or yellowish in colour
  • Whiteheads: similar to blackheads, but may be firmer and won’t be empty when squeezed
  • Papules: small red bumps that may feel tender or sore
  • Pustules: similar to papules, but with a white tip in the centre that is caused by a build-up of pus
  • Nodules: large hard lumps that can be painful
  • Cysts: large pus-filled lumps that look similar to boils and carry the greatest risk of causing permanent scarring

Do I need a prescription for this medication?

You do need a prescription for this medication in the UK.

Our healthcare professionals can provide prescriptions if they think this treatment would be right for you and your condition.

When you click the button which reads “Start Consultation” at the top of this page, you’ll see a short questionnaire set up by our healthcare team which is designed to help them understand your medical needs.

Just like an in-person consultation with your GP, our doctors will assess your answers to their questions and write a prescription for the treatment they think will be best for you.

You’ll then be able to pay for your medication and we’ll send it out to you quickly and in discreet packaging.

© 2025 Chemist4U. Innox Trading Ltd, 1 Penketh Place, Skelmersdale, Lancashire, WN8 9QX, GB. All rights reserved. Registered and regulated UK pharmacy with the GPhC (registered premises 9011784). Registered in England No. 07262043 | VAT Registration No. GB140138454