Please note: Product packaging may vary from the image shown.

Azelastine & Fluticasone Nasal Spray

Based on 2 reviews
  • Antihistamine and steroid nasal spray that relieves allergy symptoms, like hay fever 

  • Generic alterative to Dymista 

  • One spray in each nostril, morning and evening 

Pack Size
Price

1 Spray

£16.99

2 Sprays

£32.99

3 Sprays

£47.99
This treatment is inclusive of consultation & private prescription
How we are regulated
Alexandra Smith - Senior Medical Writer
Alexandra Smith
Senior Medical Writer
12/01/2026
11/01/2028
Claire Irwin - Prescribing Pharmacist
Claire Irwin
Prescribing Pharmacist
2238421

What is azelastine & fluticasone (generic Dymista) nasal spray?

This nasal spray contains two active ingredients that work together to treat moderate to severe allergies. Azelastine is an antihistamine that blocks allergic reactions, and fluticasone is a corticosteroid that reduces inflammation.

It treats seasonal allergies (like hay fever) and year-round allergies (from dust mites, mould, dust, or pets). It helps relieve a runny nose, sneezing, an itchy or blocked nose, and post-nasal drip.

What’s the difference between azelastine & fluticasone and Dymista nasal spray?

Dymista is simply the branded version of azelastine and fluticasone nasal spray. They contain the same active ingredients and work in exactly the same way, so there's no difference in effectiveness.

How does azelastine & fluticasone nasal spray work?

This nasal spray combines two ingredients that work together to treat your nasal allergy symptoms. Azelastine (an antihistamine) provides rapid relief by blocking histamine to quickly reduce sneezing, itching, and a runny nose, while fluticasone (a corticosteroid) reduces inflammation in your nasal passages for longer-lasting relief, especially from congestion.

How to use azelastine & fluticasone nasal spray 

For adults and children over the age of 12, spray once into each nostril, morning and evening.

For step-by-step images on exactly how to use this nasal spray, please refer to the patient information leaflet provided.

Azelastine & fluticasone nasal spray side effects

Common side effects of azelastine & fluticasone may include:

  • ·       nosebleed
  • ·       headache
  • ·       a bitter taste in your mouth, especially if you tilt your head backwards when you are using the nasal spray
  • ·       unpleasant smell

For more information on side effects, including potentially serious side effects, please refer to the patient information leaflet.

When to avoid azelastine & fluticasone nasal spray 

  • ·       Do not use if you’re allergic to any of the ingredients.
  • ·       This nasal spray is unsuitable for children under the age of 12.
  • ·       Rarely, this medicine causes fatigue, dizziness, or weakness. If this happens, don't drive or use machinery, and avoid alcohol as it can make these effects worse.

·       Tell your prescriber if you’re taking/using any other medicines.

Alternatives to azelastine & fluticasone nasal spray  

If you're looking for an alternative, Dymista is the branded version of azelastine and fluticasone nasal spray with the same active ingredients and effectiveness.

Other options include corticosteroid nasal sprays like Avamys for congestion, antihistamine nasal sprays like Rhinolast, or antihistamine tablets like cetirizine.

Frequently asked questions about azelastine & fluticasone nasal spray   

Is azelastine & fluticasone nasal spray available over the counter?

Azelastine and fluticasone nasal spray is a prescription-only medicine in the UK, so it's not available over the counter. You'll need to complete a consultation first, and one of our clinicians will determine if it's the right allergy treatment for you.

Does azelastine clear your sinuses?

Azelastine is an antihistamine that targets symptoms like sneezing, itching, and a runny nose rather than directly clearing sinuses. However, when combined with fluticasone (a corticosteroid), it becomes much more effective at relieving sinus congestion.

Find similar products

Azelastine & Fluticasone Nasal Spray Reviews

white-star white-star white-star white-star white-star
By Mrs C ,
June 30, 2026
It works well. Good relief from hayfever symptoms of severe sneezing
white-star white-star white-star white-star white-star
By Tekle Beyene,
June 30, 2026
It's valuable and quality spray I recommend

Advice & Guides

Cold or Hay Fever: What's the Difference? 

It's the height of summer, the sun is out, and you're reaching for yet another tissue. Is it the common cold or hay fever? Whether you're sneezing your way through a BBQ or struggling to get through the working day, feeling unwell during the warmer months is never ideal. Thankfully...
Read More

How Long Do Antihistamines Take to Work? 

Usually working within 15 minutes to an hour, antihistamine tablets can provide quick relief for hay fever or allergy symptoms. They’re easy to buy, easy to use, and can even stop you from getting symptoms entirely if you use them in time. But speed isn’t the only thing to pay...
Read More

Antihistamine Side Effects 

Antihistamines are a safe, extremely effective way of managing hay fever, allergies and some stomach and digestive conditions. Not only can they provide relief, they can actually prevent symptoms if taken early enough. However, like any medication, antihistamines can cause side effects, even if those side effects are usually mild...
Read More

Drowsy vs Non-Drowsy Antihistamines Explained

When you're dealing with hay fever, allergies, travel sickness, or insomnia, finding the right relief as quickly as possible is all that matters. But not all treatments are the same, and choosing between a drowsy or non-drowsy antihistamine can make a real difference. In this guide, we cover everything you...
Read More

Hay Fever in Babies and Children 

Many people think of hay fever as an adult problem, but it can actually affect your little ones, too. So, if your child has been sneezing, rubbing their eyes, or dealing with a runny nose every spring, hay fever could be the culprit. Thankfully, once you know what you're dealing...
Read More

Can You Take Two Antihistamines at Once?

Sometimes antihistamines are the only way to keep symptoms at bay during a high pollen hay fever season. But what do you do if one a day isn’t enough? We’ve answered all your questions about taking two antihistamines at once, including what to avoid, when to speak to a clinician...
Read More

When Does Hay Fever Season Start?

While hay fever season rolls around every year without fail, pinpointing exactly when and why it affects you can be tricky. Some people experience symptoms as early as late January, while others don't feel the effects until spring or summer. It depends on which type of pollen triggers your symptoms...
Read More

How Much Antihistamine Can You Take in 24 Hours?

Struggling with severe hay fever or allergies? We know how tempting it is to reach for another antihistamine when you’re desperate for relief. But before you do, let’s discuss whether it’s actually safe. In this guide, we’ll cover how much antihistamine you can take in 24 hours, whether you can...
Read More
© 2026 Chemist4U. Innox Trading Ltd, 1 Penketh Place, Skelmersdale, Lancashire, WN8 9QX, GB. All rights reserved. Registered and regulated UK pharmacy with the GPhC (registered premises 9012464). Registered in England No. 07262043 | VAT Registration No. GB140138454