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Ovesse 1mg/g Vaginal Cream - 15g Tube + Applicator

Based on 24 reviews
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Jacob Tilley - Medical Content Writer
Jacob Tilley
Medical Content Writer
16/10/2025
15/10/2027
Ayesha Bashir - Prescribing Pharmacist
Ayesha Bashir
Prescribing Pharmacist
2209645

Buy Ovesse 1mg/g Vaginal Cream - 15g Tube + Applicator

Ovesse contains a medicine called estriol, a type of HRT medication. It is used to relieve dryness and irritation in the vagina following the menopause.

There is a natural drop in oestrogen in women as they get older, and this drop may cause the vaginal wall to become thinner, drier and less elastic. Ovesse works by replacing the oestrogen.

Directions 

Always use Ovesse exactly as described in the patient information leaflet or as your doctor / Chemist4U pharmacist has told you.  

This medicine is for vaginal use only; you will need to fill the applicator with cream from the tube yourself. A good time to do this is before bed.

Please follow the instructions and diagrams in the patient information leaflet for how to apply the cream.

Initial dose: 1 applicator filled up to the red ring mark once a day for 2 weeks.

Maintenance dose:1 applicator filled up to the red ring mark twice a week (3 or 4 days between each dose).

Side effects 

Like all medicines, Ovesse Vaginal Cream may cause side effects in some people, but these won’t affect everybody. Common side effects may include: 

  • Irritation or itching of skin (this gets better after a few weeks)
  • Increased vaginal discharge, bleeding or spotting
  • Headaches
  • Nausea or vomiting

Please refer to the patient information leaflet for more information on side effects, including potentially serious side effects. 

Warnings

Do not use Ovesse if any of the following apply to you:

  • Are allergic to estriol or any other ingredients
  • Have or have ever had womb, ovarian or breast cancer
  • Have had any vaginal or genital bleeding since your periods stopped due to the menopause
  • Have a current vaginal infection before starting treatment
  • Have ever had a blood clot in a vein or have a blood-clotting disorder

For further information on warnings, please refer to the patient information leaflet.

Storage information 

Store below 25 °C in a cool, dry place out of sight and reach of children. Do not use after the expiry date, referring to the last day of the month stated on the packaging. Do not throw away any medicines via wastewater or household waste. 

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Ovesse 1mg/g Vaginal Cream - 15g Tube + Applicator Reviews

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By Lesley Gregory,
February 05, 2026
It does what it purports to do.
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By Chrissy,
January 27, 2026
Great service again, really fast delivery thank you
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By KIA,
January 13, 2026
Great service
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By Bracken22,
January 07, 2026
Only used for a couple of days, but feel like it's already working.
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By Chrissy,
January 06, 2026
Really fast delivery, great service
© 2026 Chemist4U. Innox Trading Ltd, 1 Penketh Place, Skelmersdale, Lancashire, WN8 9QX, GB. All rights reserved. Registered and regulated UK pharmacy with the GPhC (registered premises 9012464). Registered in England No. 07262043 | VAT Registration No. GB140138454