Imigran (Sumatriptan) Tablets

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Faye Bonnell - Medical Content Writer
Faye Bonnell
Medical Content Writer
James O'Loan - CEO & Superintendent Pharmacist
James O'Loan
CEO & Superintendent Pharmacist

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Imigran is a treatment for migraines and cluster headaches containing the active ingredient sumatriptan, a type of medicine called a 5-HT receptor agonist. Sumatriptan is not a painkiller, but it can relieve the symptoms of migraines such as headache, nausea, vomiting and sensitivity to light and sound. Imigran is recommended for adults aged 18-65.


How Imigran treats migraine symptoms

Sumatriptan is a type of medicine called a 5-HT receptor agonist. It works by releasing serotonin, a chemical in the brain, which causes the blood vessels around your brain to narrow, relieving symptoms of headaches that are thought to be caused by the widening of these blood vessels. Sumatriptan can also reduce related symptoms such as sensitivity to light or nausea.



Imigran works most effectively if you take it as soon as you feel a migraine coming on, but you can take it at any time during an attack. You shouldn’t use Imigran to prevent an attack, you must only use it when your migraine symptoms have already started. 

Adults aged between 18 and 65 will usually be advised to take one 50mg Imigran tablet, but some patients may need a 100mg dose. You should swallow your tablet whole with water. If your symptoms come back, you can take a second tablet if at least 2 hours have passed since the first tablet. You shouldn’t take a second tablet for the same attack if the first one didn’t work. You mustn’t take more than 300mg in total in any 24-hour period. 


Side effects

As with all medicines, there is the possibility of side effects when you take Imigran. These won’t affect everyone. Common side effects can include: 

  • Feeling or being sick

  • Tiredness or drowsiness 

  • Dizziness, feeling weak or getting hot flushes

  • Temporary increase in blood pressure

  • Shortness of breath

  • Aching muscles 

For more information on possible rare side effects, refer to the patient information leaflet. If you experience any side effects, including any not included in the patient information leaflet, you can report them using the MHRA Yellow Card Scheme


Serious side effects

If you experience a serious allergic reaction (may cause swelling of the face, tongue or throat, or difficulty breathing) seek medical attention immediately.

You may experience pain, heaviness, pressure or tightness in the chest, throat or other parts of the body, or unusual sensations like numbness, tingling and warmth or cold. If these effects don’t pass quickly or they become severe, particularly the chest pain, seek medical attention immediately.



You should only take Imigran if your doctor or Chemist4U pharmacist has told you it’s safe and appropriate for you to do so. You must not take Imigran if:

  • You are under 18 or over 65

  • You are allergic to sumatriptan or any of the other ingredients in this medicine

  • You have high blood pressure (unless it is mild and being treated)

  • You have or have ever had heart problems including heart attack, pain in the chest (angina) or narrowing of the arteries (ischaemic heart disease)

  • You have serious liver disease

  • You have ever had a stroke or mini-stroke (transient ischemic attack - TIA)

  • You have circulation problems in your legs that cause cramp-like pains when you walk (peripheral vascular disease)

  • You are taking any of the following anti-depressants: MAOIs (monoamine oxidase inhibitors), or have taken an MAOI in the past 2 weeks, SSRIs (selective serotonin reuptake inhibitors) or SNRIs (serotonin noradrenaline reuptake inhibitors)

  • You are taking ergotamine-type medicines, methysergide maleate or any other triptan to treat your migraines


You should talk to your doctor or Chemist4U pharmacist before taking sumatriptan if: 

  • You are pregnant, think you may be pregnant, are trying to become pregnant or if you are breastfeeding

  • You have any of the following risk factors for heart disease: high blood pressure, diabetes, you smoke or you are using nicotine substitution, your family has a history of heart disease, you are a man over 40 years of age, or you are a post-menopausal woman

  • You have kidney or liver disease

  • You use a herbal preparation containing St. John's Wort. 

  • You have a history of fits (seizures)

  • You have an intolerance to some sugars

  • You are allergic to antibiotics called sulphonamides 

  • You use Imigran / sumatriptan frequently

If you are taking any other medicines or herbal remedies, including those obtained without a prescription, speak to your doctor or Chemist4U pharmacist if you’re unsure about taking sumatriptan.


Age restrictions

Imigran should only be used by adults over the age of 18. There is not yet any evidence to support whether this medicine is safe or effective for children and adolescents under the age of 18.



It isn’t unsafe to take Imigran with food, but it’s best to take it on an empty stomach because sumatriptan can take longer to start working if you’ve just eaten.


Important information

This product is a medicine; make sure to speak to your doctor or Chemist4U pharmacist before taking this product if you have an underlying medical problem or are taking any other medicine or complementary therapy. If your symptoms get worse or continue after taking this product, contact us or your doctor. For medical services in your area, please refer to

If you are pregnant, trying to become pregnant, or breastfeeding, speak to your doctor or our pharmacist before taking this product. If you suffer from any allergies, ask your doctor or our pharmacist if this medicine is right for you.

Store all medicines out of sight and reach of children.

Please read the included leaflet carefully before using this product.

Please contact your GP if appropriate regarding this product.



Keep in the original packaging out of sight and reach of children. Do not use this medicine after the expiry date printed on the packaging, referring to the last day of the stated month. 

Frequently Asked Questions

What is a migraine?

A migraine is when you have a severe throbbing pain on one side of the head, but some people may find that the pain affects the area behind the eyes, back of the head and the neck, too. Symptoms like nausea, vomiting and an increased sensitivity to light or sound are typically signs that your headache is a migraine. Migraines are a relatively common health condition in the UK and they usually begin in early adulthood. They affect around 1 in 5 women and around 1 in every 15 men.

Do I need a prescription for this medication?

You do need a prescription for this medication in the UK.

Our healthcare professionals can provide prescriptions if they think this treatment would be right for you and your condition.

When you click the button which reads “Start Consultation” at the top of this page, you’ll see a short questionnaire set up by our healthcare team which is designed to help them understand your medical needs.

Just like an in-person consultation with your GP, our doctors will assess your answers to their questions and write a prescription for the treatment they think will be best for you.

You’ll then be able to pay for your medication and we’ll send it out to you quickly and in discreet packaging.

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