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E45 Rich Hand Cream - 50ml

Based on 7 reviews
Out of stock
Hand Cream 50ml £4.99
Olivia Appleton - Medical Content Writer
Olivia Appleton
Medical Content Writer
James O'Loan - CEO & Superintendent Pharmacist
James O'Loan
CEO & Superintendent Pharmacist

What is E45 Rich 24 Hour Hand Cream?

E45 Rich 24 hour Hand Cream provides deep moisturisation throughout the day. It is formulated with nourishing Evening Primrose Oil, which helps to lock and retain moisture within the skin. This hand cream is dermatologically tested to be suitable for dry and sensitive skin and has no added colours or fragrances. E45 provides everything to make dry skin feel good, so this rich hand cream will ensure your hands feel soft and supple all day.


What causes dry skin on your hands?

Dry skin can appear when our hands cannot maintain moisture, resulting in roughness and dehydration. In extreme conditions, this can lead to skin cracking which can result in pain, bleeding or infection. Our hands are quite resilient against the elements, but excessive exposure to harsh weather or irritants in our environments. There are several factors that can cause dry skin on the hands including:

Dry air

Without a sufficient amount of humidity in the air, our skin can become dehydrated. When temperatures drop in winter so does the humidity level. Indoor heating can also remove moisture from the air.



Not keeping ourselves hydrated throughout the day can cause our blood volume can decrease, which can cause dry skin on hands. Drinking enough water every day ensures our body is hydrated and our skin stays soft and supple from the inside.


Excessive Hand Washing

Washing our hands strips our skin of its natural oils. Washing our hands frequently throughout the day can quickly cause our hands to become dry. Using lukewarm water and a cream-based hand wash that is soap-free to reduce the drying effects. Use hand cream liberally after washing hands to keep them hydrated.



Some medications, such as topical treatments for acne, can contain chemical exfoliants like, retinol, glycolic acid, salicylic acid and benzoyl peroxide. These chemicals can severely dry out our skin, including our hands.


An underlying condition

There are a few medical conditions that can cause dry skin on our hands, including:

  • Atopic dermatitis (eczema)
  • Psoriasis
  • Diabetes
  • Underactive thyroid gland

If you suspect your dry skin symptoms are caused by a medical condition, seek medical advice from GP or a Chemist 4 U pharmacist.


Your genes

There is research that suggests dry skin can be inherited. Gene mutations which control the production of proteins used to form and hydrate the skin’s barrier, can cause several drying skin conditions.


Why should we take care of our hands?

We know that moisturising our face and body is important to fight dry skin, replenish our skin’s protective barrier and keep our skin soft and supple, the same applies to our hands. We wash our hands many times a day and use them in many tasks which can take their toll on the skin on our hands. Using a hand moisturiser such as E45 Rich Hand Cream keeps them hydrated throughout the day and helps to prevent dry skin, cracks and irritation.


How does E45 Hand Cream work?

E45 Hand Cream is formulated with Evening Primrose Oil, a deeply nourishing ingredient to provide deep and long-lasting moisturisation. This luxuriously rich hand cream helps to lock and retain moisture within the skin for 24 hours. The lightweight formula is quickly absorbed by the skin for easy application. It contains no perfumes or colours that can irritate the skin and is dermatologically tested to be suitable for dry and sensitive skin.

What is Evening Primrose Oil?

Evening Primrose Oil is used in skincare and cosmetics to enhance lipid (our skin’s natural fats) content and increase hydration in our skin. Evening Primrose Oil can increase water retention and an improvement in the skin’s moisture levels. This hydration improves the skin barrier function which can have a soothing effect for dry, uncomfortable skin.

How to use this product

Apply as required, daily. Ensure to apply after washing to replenish moisture.


When NOT to use this product

Do NOT use this product if you are allergic to any of the listed ingredients (see ingredients tab for full list). This product is for external use. Avoid contact with eyes. If contact occurs, rinse thoroughly with clean water. Always check the label before applying any new topical product to your skin, to ensure it is suitable for you. If you are unsure whether this product meets your needs, speak to your GP or a Chemist 4 U Pharmacist


Side Effects

Everybody’s skin is different, so the use of any topical product can cause an allergic reaction, although not everyone will experience this. If you experience any symptoms of an allergic reaction, such as a rash or swelling, discontinue use immediately and seek advice from your GP


Important Information

Make sure to speak to your doctor or Chemist 4 U pharmacist before using this product if you have an underlying medical problem or are taking any other medicine or complementary therapy. If your symptoms get worse or continue after taking this product, contact us or your doctor. For medical services in your area, please refer to

If you are pregnant, trying to become pregnant, or breastfeeding, speak to your doctor or our pharmacist before taking this product. If you suffer from any allergies, ask your doctor or our pharmacist if this medicine is right for you.

Store all medicines out of sight and reach of children.

Please read the included leaflet carefully before using this product.

Please contact your GP if appropriate regarding this product.


E45 Rich Hand Cream - 50ml Reviews

By Caroline,
August 22, 2023
Not as good as was hoping for. Disappointed
By Noel Parker,
January 04, 2022
Really good product.
By Kathleen Kittle,
December 21, 2021
This E45 cream is very rich and easy to use. Don't need very much - it leaves the skin feeling soft and not greasy which is great. Works well on dry hands almost immediately.
By Valerie Simpson,
October 13, 2021
Hands often chapped - good for soothing
By Ingrid Higgins,
May 11, 2021
Excellent for winter/gardening hands

Advice & Guides

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If you have dry skin that always seems to happen in the same area and drives you up the wall with that itchy, scratchy feeling, then you could have eczema.

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