Zoely Tablets


  • Combined contraceptive pill
  • Used to prevent pregnancy
  • Contains the hormones nomegestrol acetate (a progestogen) and estradiol (an oestrogen)
Upon completion of a medical consultation with one of our health care professionals you can expect prices to start from £36.99
Prescription Included
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All inclusive price starts from £36.99
The treatment is inclusive of consultation, private prescription & medicine delivery
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Alexandra Moses - Medical Content Writer
Alexandra Moses
Medical Content Writer
James O'Loan - CEO & Superintendent Pharmacist
James O'Loan
CEO & Superintendent Pharmacist

Buy Zoely Tablets

Zoely is a combined contraceptive pill that’s used to prevent pregnancy. Each pill contains a small amount of two different female hormones that are produced by your ovaries during your menstrual cycle.

These are nomegestrol acetate (a progestogen) and estradiol (an oestrogen). The 4 yellow tablets are inactive tablets that do not contain hormones and are called placebo tablets. 

The contraceptive pill will not protect you against sexually transmitted diseases (STIs); to prevent both pregnancy and STIs, it’s advised that you wear a condom.



Always take Zoely exactly as described in the patient information leaflet or as your doctor / Chemist4U pharmacist has told you. The Zoely blister pack contains 28 tablets: 24 white tablets containing both oestrogen and progesteron hormones, and 4 yellow tablets containing no hormones. 

Each time you start a new blister pack of Zoely, take the number 1 white active tablet in the left-hand top corner. The day of the week is printed next to each tablet. If, for example, you start on a Wednesday, take a tablet with "WED'' next to it. Stick it on the blister, just above the row of white active tablets where it reads ‘Place day label here’. This allows you to check whether you took your daily tablet. 

Take one tablet each day at about the same time, with some water if necessary. Follow the direction of the arrows on the blister pack, so use the white active tablets first and then the yellow placebo tablets. Your period will start during the 4 days that you use the yellow placebo tablets (this is known as withdrawal bleeding). 

Usually this withdrawal bleed will start 23 days after the last white active tablet and may not have finished before the next blister pack is started. Start taking your next blister pack immediately after the last yellow tablet, even if your period hasn’t finished. This means that you will always start a new blister pack on the same day of the week, and also that you have your period on roughly the same days each month. 

Some users may not have their period every month during the intake of the yellow tablets. If you have taken Zoely every day according to these directions, it is unlikely that you are pregnant.

If you vomit within 3-4 hours of taking a white active tablet, or you have severe diarrhoea, the active ingredients of your Zoely tablet may not have been completely absorbed into your body. The situation is similar to if you forget a white active tablet. 

After vomiting or diarrhoea, you must take another white active tablet from a reserve blister pack as soon as possible. If possible take it within 24 hours of when you normally take your pill. Take the next tablet at the usual time. You should use another method of contraception, like a condom, if you experience vomiting or diarrhoea.


Starting your first pack of Zoely

When no hormonal contraceptive has been used in the past month, start taking Zoely on the first day of your cycle (i.e. the first day of your menstrual bleeding). Zoely will work immediately. You do not need to use an additional contraceptive method.

When changing from another combined hormonal contraceptive (combined pill, vaginal ring, or transdermal patch), you can start taking Zoely the day after you have taken the last tablet from your present pill blister pack (this means no tablet-free break). 

If your present pill blister pack also contains inactive (placebo) tablets you can start Zoely on the day after taking the last active tablet (if you are not sure which this is, ask your doctor or pharmacist). You can also start later, but never later than the day following the tablet-free break of your present pill (or the day after the last inactive tablet of your present pill). 

In case you use a vaginal ring or transdermal patch, it is best to start using Zoely on the day you remove the ring or patch. You can also start, at the latest, on the day you would have started using the next ring or patch. If you follow these instructions, it is not necessary to use an additional contraceptive method. 

When changing from a progestogen-only pill (mini pill), you can stop taking the mini pill any day and start taking Zoely the next day. But if you are having intercourse, make sure you also use a barrier method of contraception for the first 7 days that you are taking Zoely. 

When changing from a progestogen-only injectable, implant or a hormone-medicated intrauterine system (IUS), start using Zoely when your next injection is due or on the day that your implant or IUS is removed. But if you are having intercourse, make sure you also use a barrier method of contraception for the first 7 days that you are taking Zoely. 

After having a baby, you can start Zoely between 21 and 28 days after having a baby. If you start later than day 28, you should also use a barrier method of contraception during the first 7 days of Zoely use. If, after having a baby, you have had sexual intercourse before starting Zoely, be sure that you are not pregnant or wait until your next menstrual period. 

If you want to start Zoely after having a baby and are breastfeeding, ask your doctor what to do if you are not sure when to start. After a miscarriage or an abortion, always follow the advice of your doctor.


Side effects

Like all medicines, Zoely may cause side effects in some people, but these won’t affect everybody. Common side effects include: 


  • Acne
  • Changes to menstrual periods (e.g. absence or irregularity)
  • Heavy menstrual periods
  • Decreased interest in sex
  • Depression/depressed mood
  • Mood changes
  • Headache or migraine
  • Feeling sick (nausea)
  • Pelvic pain
  • Weight gain


For more information on potential side effects, refer to the patient information leaflet. If you experience any side effects, including any not included in the patient information leaflet, you can report them using the MHRA Yellow Card Scheme.


Serious side effects

Seek emergency medical attention if you notice any signs of a severe allergic reaction, symptoms of which include swelling of the face and throat, skin rash, breathing difficulties and/or loss of consciousness. 

The use of combined hormonal contraceptives has been connected with an increase in the risk of blood clots in the vein (venous thrombosis). However, these side effects are rare. Most frequently, they occur in the first year of using a combined hormonal contraceptive.

About 5-7 out of 10,000 women taking the combined pill experience a blood clot. Your personal medical history can also play a role in how likely you are to experience a blood clot. For more information regarding the risk of blood clots with this medicine, please refer to the patient information leaflet.

The risk of certain cancers is higher in women who take the combined contraceptive pill, like breast cancer and cervical cancer, but it is still rare.



Zoely may be unsuitable for certain people. Do not take these tablets if you are allergic to estradiol, nomegestrol acetate or any of the other listed ingredients. Do not take these tablets if you have any of the following:


  • If you have (or have ever had) a blood clot in a blood vessel of your legs (deep vein thrombosis, DVT), your lungs (pulmonary embolism, PE) or other organs
  • If you know you have a disorder affecting your blood clotting - for instance, protein C deficiency, protein S deficiency, antithrombin – III deficiency, Factor V Leiden or antiphospholipid antibodies
  • If you need an operation or if you are off your feet for a long time
  • If you have ever had a heart attack or a stroke
  • If you have (or have ever had) angina pectoris (a condition that causes severe chest pain and may be a first sign of a heart attack) or transient ischaemic attack (TIA – temporary stroke symptoms)
  • If you have any of the following diseases that may increase your risk of a clot in the arteries: severe diabetes with blood vessel damage, very high blood pressure, a very high level of fat in the blood (cholesterol or triglycerides), a condition known as hyperhomocysteinaemia
  • If you have (or have ever had) a type of migraine called ‘migraine with aura’
  • If you have (had) inflammation of the pancreas (pancreatitis) associated with high levels of fat in your blood
  • If you have (had) severe liver disease and your liver is not yet working normally
  • If you have (had) a benign or malignant tumour in the liver
  • If you have (had), or if you may have, cancer of the breast or the genital organs
  • If you have meningioma or have ever been diagnosed with a meningioma (a generally benign tumour of the tissue layer between the brain and the skull)
  • If you have any unexplained bleeding from the vagina


Using/taking other medicines

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription and herbal medicines. 

There are medicines that can make Zoely less effective in preventing pregnancy, or can cause unexpected bleeding. These include medicines used to treat:


  • Epilepsy (e.g. primidone, phenytoin, phenobarbital, carbamazepine, oxcarbazepine, topiramate, felbamate)
  • Tuberculosis (e.g. rifampicin)
  • HIV infections (e.g. rifabutin, ritonavir, efavirenz)
  • Hepatitis C virus (HCV)
  • Infection (e.g. boceprevir, telaprevir)
  • Other infectious diseases (e.g. griseofulvin)
  • High blood pressure in the blood vessels in the lungs (bosentan)


The herbal product St. John’s wort may also stop Zoely from working properly. If you want to use herbal products containing St. John’s wort while you are already using Zoely you should consult your healthcare provider first.

If you are taking medicines or herbal products that might make Zoely less effective, a barrier contraceptive method should also be used. Since the effect of another medicine on Zoely may last up to 28 days after stopping the medicine, it is necessary to use the additional barrier contraceptive method for that long.


Age restrictions 

We can only supply Zoely to women aged 18 years and over from our private clinic.


Storage information

Store in a cool, dry place out of sight and reach of children. Do not use after the expiry date, referring to the last day of the month stated on the packaging. Do not throw away any medicines via wastewater or household waste.


Important information

This product is a medicine; make sure to speak to your doctor or Chemist4U pharmacist before taking this product if you have an underlying medical problem or are taking any other medicine or complementary therapy. If your symptoms get worse or continue after taking this product, contact us or your doctor. For medical services in your area, please refer to https://www.nhs.uk

If you suffer from any allergies, ask your doctor or Chemist4U pharmacist if this medicine is right for you.

Store all medicines out of sight and reach of children.

Please read the included leaflet carefully before using this product.

Please contact your GP if appropriate regarding this product.

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