Based on 5 reviews

Available in 80g

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Alexandra Moses - Medical Content Writer
Alexandra Moses
Medical Content Writer
James O'Loan - CEO & Superintendent Pharmacist
James O'Loan
CEO & Superintendent Pharmacist

Buy Oestrogel

Oestrogel is a type of hormone replacement therapy (HRT) used to relieve postmenopausal symptoms such as hot flushes. Oestrogel can also be used for the prevention of osteoporosis (fragile bones), which affects some women after the menopause. 


How Oestrogel works

The active ingredient in Oestrogel is oestradiol, which is a type of the female sex hormone oestrogen. Levels of oestrogen naturally drop during menopause, so taking a treatment like estradiol replaces these lost hormones and helps to relieve symptoms associated with menopause. This type of treatment is referred to as hormone replacement therapy (HRT).



Always take this medicine exactly as described in the patient information leaflet or as your doctor or pharmacist has told you. ­If you have never used any other HRT medicines or you are switching to Oestrogel from a period-free HRT product, you can start using Oestrogel on any convenient day. If you are currently using another type of HRT where you have a period, finish your current medicine pack before you start using Oestrogel.


Before using your new Pump Pack for the first time, you need to prepare it for use as follows:


  • Remove the cap from the canister.
  • Press the plunger down a few times until the gel comes out.
  • Do not use this first dose of gel from your Pump Pack. This dose should be discarded.


Apply the gel once a day, either in the morning or evening. Try to use the gel at about the same time each day. Your doctor will prescribe the lowest dose for the shortest time to treat your symptoms. One pump is equal to one measure. The usual daily dose is 2 measures (i.e. 2 pumps) of gel. In this case, the Pump Pack will last four weeks.


Make sure that your hands and the skin where you are going to apply the gel are clean, dry and unbroken. Remove the canister cap to reveal the plunger. Hold the Oestrogel Pump Pack in one hand and place your other hand under the spout, ready to collect the gel. Push the plunger down firmly. This will dispense one measure of the gel. Apply the gel to either  the outer arm and shoulder of both arms, or the mid-inner thigh of both legs. Do not apply on or near the breasts, or near the genital area. If your doctor has prescribed 2 measures of gel, spread 1 measure over each outer arm and shoulder, or each mid-inner thigh. If 4 measures of gel have been prescribed, spread 2 measures over each outer arm and shoulder or each mid-inner thigh. Leave to dry for 5 minutes before covering with clothes. Wash hands with soap and water after applying the gel. 


Side effects 

Like all medicines, Oestrogel can cause side effects, but these won’t affect everyone. Side effects include: 


  • Painful periods
  • Menstrual periods which are heavier or last longer than usual
  • Abnormal or irregular bleeding
  • White or yellow vaginal discharge
  • Mood swings
  • Migraine
  • Verigo
  • Wind
  • Increase in the volume of the uterus 
  • Vaginal yeast infection
  • Feeling of weakness


For more information about potential side effects, refer to the patient information leaflet. If you experience any side effects, including any not included in the patient information leaflet, you can report them using the MHRA Yellow Card Scheme


Serious side effects


The following diseases are reported more often in women using HRT medicines which circulate in the blood compared to women not using HRT. These risks apply less to vaginally administered treatments such as Oestrogel:


  • Ovarian cancer
  • Blood clots in the veins of the legs or lungs
  • Stroke
  • Probable memory loss if HRT is started over the age of 65


For more detailed information about these risks, refer to the patient information leaflet. 



Do not use Oestrogel if: 


  • You have ever had breast cancer
  • You have any unexplained 
  • You have excessive thickening of the womb lining (endometrial hyperplasia) that is not being treated 
  • You have ever had a blood clot in a vein (thrombosis) such as in the legs (deep vein thrombosis) or lungs (pulmonary embolism) 
  • You have a blood clotting disorder (such as protein C, protein S or antithrombin deficiency) 
  • You have or recently have had a disease caused by blood clots in the arteries such as a heart attack, stroke or angina 
  • You have ever had a liver disease and your liver function tests have not returned to normal
  • You have a rare blood problem called porphyria 
  • You are allergic to any of the ingredients in this medicine 


Talk to your doctor before taking Oestrogel if you have any of the following conditions: 


  • Fibrosis inside your womb
  • Growth of womb lining outside your womb (endometriosis) or a history of excessive growth of the womb lining (endometrial hyperplasia)
  • Increased risk of developing blood clots
  • Increased risk of getting an oestrogen-sensitive cancer (such as having a mother, sister or grandmother who has had breast cancer)
  • High blood pressure
  • A liver disorder, such as a benign liver tumour
  • Diabetes
  • Gallstones
  • Migraine or severe headaches
  • A disease of the immune system that affects many organs of the body (Systemic Lupus Erythematosus, SLE)
  • Epilepsy
  • Asthma
  • A disease affecting the eardrum and hearing (otosclerosis)
  • A very high level of fat in your blood (triglycerides)
  • Fluid retention due to heart or kidney problems.


Stop using Oestrogel and see a doctor immediately if you notice any of the following:


  • Yellowing of your skin or the whites of your eyes (jaundice). These may be signs of a liver disease
  • A large rise in your blood pressure (symptoms may be headache, tiredness, dizziness)
  • Migraine-like headaches which happen for the first time
  • Pregnancy
  • Signs of a blood clot, such as painful swelling and redness of the legs, sudden chest pain, difficulty in breathing


Important information

This product is a medicine; make sure to speak to your doctor or Chemist4U pharmacist before taking this product if you have an underlying medical problem or are taking any other medicine or complementary therapy. If your symptoms get worse or continue after taking this product, contact us or your doctor. For medical services in your area, please refer to https://www.nhs.uk

If you are pregnant, trying to become pregnant, or breastfeeding, speak to your doctor or our pharmacist before taking this product. If you suffer from any allergies, ask your doctor or our pharmacist if this medicine is right for you.

Store all medicines out of sight and reach of children.

Please read the included leaflet carefully before using this product.

Please contact your GP if appropriate regarding this product.


Helpful Advice on Medication Restrictions & Addiction

For further information on our medication restrictions policy, please click here.

If you are concerned about addiction to 'over the counter' medication, we urge you to visit the below links for professional help and advice:

NHS Help & Advice on Drug Addiction

Talk To Frank - Drug Addiction Help & Support


Oestrogel-Pump Reviews

By Isabelle Jolly,
February 06, 2024
Genuine sealed product which i need and helps me through menopause
By Rebecca Hobbs,
November 15, 2021
Helps with menapause
By Jane Sheppard,
October 12, 2021
Faat efficient service.
By Karla,
October 12, 2021
Good product
By Karla,
October 05, 2021
Pain to put it on, very cold

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