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Available in multiple pack sizes

  • Non-steroidal anti-inflammatory drug (NSAID).
  • Cheaper generic alternative Naproxen available
  • Contains naproxen to relieve pain and inflammation.
  • Always read the patient information leaflet before use. 
The treatment is inclusive of consultation, private prescription & medicine delivery
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Faye Bonnell - Medical Content Writer
Faye Bonnell
James O'Loan - CEO & Superintendent Pharmacist
James O'Loan
CEO & Superintendent Pharmacist
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Naprosyn is a medicine containing the active ingredient naproxen, a type of drug known as a Non Steroidal Anti Inflammatory Drug (NSAID). This medicine is used to relieve pain, swelling, redness and heat (inflammation), and it can treat problems with your muscles, joints and tendons, sprains, gout, ankylosing spondylitis (pain and stiffness in the neck and back) or arthritis. It can also be used to treat period pain in women. 


How naproxen relieves pain

Naprosyn contains the active ingredient naproxen, a type of medicine known as a Non Steroidal Anti Inflammatory Drug (NSAID). Naproxen works by blocking the effect of some chemicals in your body called cyclo-oxygenase enzymes, which help to make other chemicals called prostaglandins that are produced in areas of damage or injury. These prostaglandins produce pain and inflammation, so by blocking them, these symptoms can be reduced. 



To treat muscle, joint or tendon problems and period pain, the usual dose for adults is 500mg, followed by a 250mg tablet every 6 to 8 hours. For arthritis and ankylosing spondylitis, the usual dose is between 500mg and 1000mg and this can be taken all at once or split into two and taken twice a day. For gout, the usual starting dose is 750mg followed by a 250mg tablet every 8 hours as needed. 

Older people and people with liver and kidney problems should consult their doctor or Chemist4U pharmacist for advice, as a lower dosage will most likely be required. 

Children aged 5 years and over can take Naprosyn for rheumatoid arthritis. This usual dose in this case is 10mg per kg of body weight each day, and the dose is split into two and given 12 hours apart. 

You should always swallow the tablets whole with water - do not try to crush or chew them. Naprosyn should always be taken with or after food, so you should avoid taking these tablets on an empty stomach. 


Side effects

Like all medicines, there is a possibility you may experience side effects when you take Naprosyn, but these won’t affect everyone. Side effects can include: 

  • Heartburn, indigestion, stomach ache, feeling or being sick, constipation, diarrhoea or wind

  • Blood problems like anaemia or changes to the numbers of white blood cells

  • Depression, difficulty sleeping, confusion or hallucinations

  • Headache, fits, feeling dizzy or sleepy, pins and needles or numbness of your hands and feet or difficulty with your memory or concentration

  • Changes to your eyesight or hearing, eye pain, tinnitus or dizziness that causes problems with your balance

  • Swelling of your hands, feet or legs with chest pains, tiredness and shortness of breath, a fluttering feeling in your heart, slow heartbeat or high blood pressure. 

  • Problems with the way your heart pumps blood around the body or damage to your blood vessels (symptoms include tiredness, shortness of breath, feeling faint and general pain) 

  • Difficulty breathing, shortness of breath, wheezing, coughing, pneumonia or swelling of your lungs

  • Skin rashes including redness, hives, pimples and blisters on your body or face, bruising, itching, sweating, hair loss or your skin being more sensitive to the sun

  • Blood in your urine or kidney problems

  • Thirst, fever, feeling tired or generally unwell

  • A sore mouth or mouth ulcers

  • Muscle pain or weakness

  • Systemic lupus erythematosus (symptoms of SLE include fever, rash, problems with your kidneys and joint pain)

If you experience any side effects, including any not included in the patient information leaflet, you can report them using the MHRA Yellow Card Scheme


Serious side effects

If you experience any symptoms of the following severe side effects, seek medical attention immediately: 

  • A severe allergic reaction (swelling of the face, tongue or throat, skin rash or difficulty breathing) seek medical attention immediately.

  • Serious stomach or gut problems (vomiting blood or bits that look like coffee grounds, bleeding from your back passage, severe stomach pain, nausea or fever)

  • Severe skin rashes (blisters or peeling of your skin in your mouth, throat or eyes)

  • Liver problems (yellowing of your skin or whites of your eyes [jaundice], feeling tired, loss of appetite, feeling or being sick and pale coloured stools) 

  • Heart attack (chest pain which may spread to your neck and shoulders and down your left arm)

  • Stroke (muscle weakness and numbness on one side of your body, confusion and an altered sense of smell, taste, hearing or vision)

  • Meningitis (fever, feeling or being sick, a stiff neck, headache, sensitivity to bright light and confusion) 



You should only take Naprosyn if your doctor or Chemist4U pharmacist has told you it’s safe and appropriate for you to do so. You must not take Naprosyn if:

  • You are allergic to naproxen or any of the other ingredients in this medicine

  • You are allergic to aspirin, other NSAIDs or any other pain relief medicines such as ibuprofen or diclofenac

  • You have or have ever had any problems with your stomach or intestine, like an ulcer or bleeding

  • You have previously experienced bleeding or perforation in your stomach while taking NSAIDs

  • You have severe problems with your kidneys, liver or heart

  • You are in the last three months of pregnancy 

Naprosyn should be taken with caution if you have certain underlying health conditions. You should talk to your doctor or Chemist4U pharmacist before taking this medicine if: 

  • You are taking any other medicines or herbal remedies, including those obtained without a prescription

  • You have ever had heart problems or a stroke, or you’re at risk of these conditions due to high blood pressure, diabetes, high cholesterol or smoking for example

  • You have Asthma or allergies or have ever had swelling of the face, lips, eyes or tongue in the past

  • You have a feeling of weakness due to an illness or being an older person

  • You have lumps in your nose (polyps) or you sneeze a lot or have a runny, blocked or itchy nose (rhinitis)

  • You have problems with your kidneys or liver

  • You have problems with the way that your blood clots or problems with your blood vessels (arteries) anywhere in your body

  • You have too much fat in your blood (hyperlipidaemia)

  • You have an autoimmune condition such as systemic lupus erythematosus (SLE), ulcerative colitis or Crohn’s disease


Pregnancy and breastfeeding

You should not take Naprosyn if you are in the last three months of your pregnancy as it could cause harm to your baby. You should speak to your doctor or Chemist4U pharmacist for advice if you are pregnant, think you may be pregnant, are planning to have a baby or are breastfeeding. Naprosyn could make it more difficult for you to become pregnant.


Important information

This product is a medicine; make sure to speak to your doctor or Chemist4U pharmacist before taking this product if you have an underlying medical problem or are taking any other medicine or complementary therapy. If your symptoms get worse or continue after taking this product, contact us or your doctor. For medical services in your area, please refer to

If you are pregnant, trying to become pregnant, or breastfeeding, speak to your doctor or our pharmacist before taking this product. If you suffer from any allergies, ask your doctor or our pharmacist if this medicine is right for you.

Store all medicines out of sight and reach of children.

Please read the included leaflet carefully before using this product.

Please contact your GP if appropriate regarding this product.



Store below 30°C and keep in the original packaging out of sight and reach of children. Do not use this medicine after the expiry date printed on the packaging, referring to the last day of the stated month. 



  • The active substance in Naprosyn 250 mg and 500 mg Tablets is naproxen. Each tablet contains either 250 mg (milligrams) or 500 mg of naproxen. The other ingredients in the tablets are povidone, magnesium stearate, croscarmellose sodium, water and iron oxide (E172).

Drug Data
Product Type
Prescription Only
Brand Information
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Brand Address
Sovereign House, Miles Gray Road, Basildon, Essex SS14 3FR
01268 943700

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Shipping Times

MethodHandling TimeTransit TimeTimescaleApprox Cost
Standard Shipping (3-5 Working Days)123£2.95

Times are given in working days and are approximate. Costs may change based on order total, day of the week or location within the UK. Ability to hit timescales will depend on whether the products are ordered before a cut off time, as well as additional administration time incurred in reviewing your order.

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Shipping Costs

Free UK Delivery on all orders over £30* - Delivery within 3-5 working days.

Standard UK Delivery - £2.95* - Delivery within 3-5 working days.

Express UK Delivery - £4.95** - Delivery within 1-2 working days.

Temperature Controlled Delivery - £8.85 - Delivery within 1-3 working days.

Please Note: These prices are shown as a guide only. All delivery times are approximate but have been obtained in good faith.

*Excluding refrigerated products and treatments which are subject to different postage charges.


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We respect that many of our products are of a sensitive nature - this is why we take every step to keep your purchases private.

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Frequently Asked Questions
You do need a prescription for Naprosyn in the UK. Our healthcare professionals can provide prescriptions if they think this treatment would be right for you and your condition. When you click the button which reads “Start Consultation” at the top of this page, you’ll see a short questionnaire set up by our healthcare team which is designed to help them understand your medical needs. Just like an in-person consultation with your GP, our doctors will assess your answers to their questions and write a prescription for the treatment they think will be best for you. You’ll then be able to pay for your medication and we’ll send it out to you quickly and in discreet packaging.