Benadryl Allergy Relief Plus Decongestant Capsules – 12 Capsules

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Laura Henderson - Medical Content Writer
Laura Henderson
Medical Content Writer
James O'Loan - CEO & Superintendent Pharmacist
James O'Loan
CEO & Superintendent Pharmacist

What is Benadryl Allergy Relief Plus Decongestant?

Benadryl Allergy Relief Plus Decongestant capsules are a treatment for allergy symptoms that can also help to clear a blocked or runny nose. If you find that congestion is a regular problem for you during hay fever season or after you’ve come into contact with pet fur or dust mites, this treatment can help to clear your airways while managing your other allergy symptoms. Benadryl Plus can be taken by adults and children over the age of 12, ideal for when your allergies are making you uncomfortable and you need a reliable way to clear that blocked nose and reduce pressure in your sinuses.

What is hay fever?

Hay fever is an allergy to pollen, which is created by plants over the spring and summer months. If you get pollen into your system, your body will respond and try to get rid of it, creating a natural substance called histamine to trigger allergic symptoms. This leaves you experiencing irritating symptoms like sneezing, coughing, a blocked nose, or itching.

Why do I get a blocked nose when I have hay fever?

Lots of people get a blocked or runny nose during hay fever season, and like all of your other symptoms, it happens because your body is trying to protect itself from pollen. The blood vessels in your nose can swell up when you have an allergic reaction, making your nasal passages narrower and making it more difficult for you to breathe. Because the amount of space in your nose is reduced, the built up mucus in your nose has nowhere to go but out, causing a runny nose and making you sneeze.

How will Benadryl Allergy Relief Plus Decongestant help to ease my allergy symptoms and congestion?

Benadryl Allergy Relief Plus Decongestant capsules use two active ingredients to ease congestion and other allergy symptoms. The first ingredient, acrivastine, is an antihistamine, which blocks the histamine produced in your body due to allergies, relieving allergy symptoms quickly. The second ingredient is pseudoephedrine, a decongestant which reduces swelling in your nasal passages and sinuses, clearing your airways and reducing pressure in your head. This combination of ingredients is especially effective if your allergies cause a blocked or runny nose, sneezing, watery eyes, or itchy eyes, nose, ears, or throat.

Can I take this product if I’m pregnant?

If you’re pregnant or breastfeeding you should speak to your doctor or pharmacist before taking Benadryl capsules. This product may not be the best treatment for you or your baby at this time, and a medical professional may want to recommend another medication for you.

Can I take this treatment if I’m taking any other medication?

If you’re taking any other medications, you should speak to your doctor or pharmacist before taking Benadryl Plus Decongestant capsules. You should not take this product if you are already taking:

  • Beta blockers, used for high blood pressure

  • Stimulants, appetite suppressants, or drugs used to treat congestion or asthma

  • MAOIs (Monoamine Oxidase Inhibitors) or RIMAs (Reverse Inhibitors of Monoamine Oxidase), which are used for depression, especially if you have taken these within the past 2 weeks

  • Any cough or cold medicines

Speak to your doctor or pharmacist before taking this product if you are already taking:

  • Antihypertensives, which are used to treat high blood pressure, e.g. guanethidine, methyldopa, adrenergic neurone blockers and beta blockers, debrisoquine, bretylium, betanidine

  • Sedatives and tranquilisers, used for anxiety or sleep disorders

  • Tricyclic antidepressants, used for mood disorders

  • Anticholinergic drugs, used for cramps or spasms

  • Ketoconazole, an antifungal used for fungal infections

  • Erythromycin, an antibiotic used for bacterial infections

  • Moclobemide, used for mood disorders

  • Cardiac glycosides, used to control heart rhythms or contractions, such as digoxin

  • Ergot alkalides, used to treat migraines, such as ergotamine or methysergide

  • Oxytocin, which is used to help contractions during childbirth

Will this antihistamine make me drowsy?

Benadryl Plus Decongestant capsules can make you feel drowsy or dizzy after taking them. If you experience this or any other symptoms which could affect your attention you should not attempt to drive or use any other tools or machinery until you’re sure that the symptoms have passed and you’re safe to do so.

How to take Benadryl Plus capsules

Take one Benadryl Plus capsule up to 3 times a day, taking no more than 3 capsules a day. Swallow the capsule whole with a sip of water or another cool drink.

When should this product not be used?

Benadryl Allergy Relief Plus Decongestant capsules are not suitable for children under the age of 12 or adults over the age of 65. Do not use this product if you are allergic to pseudoephedrine hydrochloride, acrivastine, the antihistamine triprolidine, or any of the other listed ingredients. Do not take this product if you have:

  • High blood pressure or heart disease

  • Diabetes

  • Phaeochromocytoma, a rare tumour which affects your heart rate or blood pressure

  • Glaucoma

  • An overactive thyroid gland

  • Severe kidney problems

Speak to your doctor or pharmacist before taking this product if you have:

  • Kidney or liver problems

  • A thyroid disorder

  • Prostate problems

  • Alcohol dependence

  • Blocked arteries or veins

  • Emphysema, chronic bronchitis, acute or chronic bronchial asthma

Does Benadryl Allergy Relief Plus Decongestant have any side effects?

Like all medications, Benadryl Allergy Relief Plus Decongestant capsules can have side effects, although not everyone will experience them. If you experience any of the following side effects you should stop use and seek immediate medical assistance:

  • Sudden fever, reddening of the skin, many small pustules

  • Severe headache, feeling sick, being sick, confusion, fits, visual disturbances

  • Allergic reactions, e.g. skin rashes, hives, severe blistering or peeling of the skin, itching

  • Hallucinations, paranoid delusions

  • Swelling of the face, lips, mouth, tongue, or throat, difficulty breathing or swallowing

  • Inflammation of the colon, causing symptoms such as sudden abdominal pain or rectal bleeding

  • A fast or irregular heartbeat or palpitations

  • Restlessness or sleep disturbances

  • Trouble peeing, especially in men with prostate problems

Other common side effects of this product include:

  • Headache, drowsiness

  • Difficulty sleeping, nervousness, dizziness

  • Dry mouth, geeling sick

If you experience these or any other side effects while taking this medication, you should speak to your doctor or pharmacist right away. For more information about reporting the side effects of medication, please see the MHRA’s Yellow Card Scheme.

How to store this product

Store in a cool, dry place which is below 25 degrees C. Do not take this product if the expiry date printed on the original packaging. Keep out of sight and reach of children.

Important Information

This product is a medicine; make sure to speak to your doctor or Chemist 4 U pharmacist before taking this product if you have an underlying medical problem or are taking any other medicine or complementary therapy. If your symptoms get worse or continue after taking this product, contact us or your doctor. For medical services in your area, please refer to

If you are pregnant, trying to become pregnant, or breastfeeding, speak to your doctor or our pharmacist before taking this product. If you suffer from any allergies, ask your doctor or our pharmacist if this medicine is right for you.

Store all medicines out of sight and reach of children.

Please read the included leaflet carefully before using this product.

Please contact your GP if appropriate regarding this product.


Helpful Advice on Medication Restrictions & Addiction

For further information on our medication restrictions policy, please click here.

If you are concerned about addiction to 'over the counter' medication, we urge you to visit the below links for professional help and advice:

Benadryl Allergy Relief Plus Decongestant Capsules – 12 Capsules Reviews

By Gary M,
July 02, 2022
I find this to be the best product for clearing my sinuses. I generally use it a couple of times a week for best effect.
By Christina Adams,
July 06, 2020
The only anti-histamine that work for me.

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