Aciclovir Cream

Effectively Treat and Prevent Cold Sores

  • Aciclovir cold sore cream
  • Antiviral cream to treat viral infections
  • Can also be used to treat genital herpes
  • Always read the patient information leaflet before use
The treatment is inclusive of consultation, private prescription & medicine delivery
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Laura Henderson - Medical Content Writer
Laura Henderson
Medical Content Writer
James O'Loan - CEO & Superintendent Pharmacist
James O'Loan
CEO & Superintendent Pharmacist

Buy Aciclovir Cream

Aciclovir cream is a treatment for cold sores or genital herpes, an antiviral that can help to combat the virus that causes these conditions. It helps to make your sores less severe and helps them to heal more quickly, ideal for those who find that their condition is particularly severe or keeps coming back. Apply the cream directly to your skin 5 times a day and let it do its work helping your immune system to tackle the virus lurking in your skin.


How aciclovir cream works

Aciclovir is an antiviral medication that can be used to treat both cold sores and genital herpes. You start to use it at the very first signs of a blister or sore popping up, usually a tell-tale itching or tingling sensation, and apply it to the area where it can get to work. It helps to keep the virus from replicating so it won’t grow, helping to keep your sores from being severe and helping them to clear up more quickly. Although it won’t cure the virus completely, it can help your immune system to deal with a flare-up and keep it under control.



Your doctor will let you know how much aciclovir cream you should use, but you will usually use it as follows. Before using this product you should wash your hands thoroughly. Apply a thin layer of cream over the affected area, whether you’re treating a cold sore or genital herpes, the application is the same. Make sure that you don’t apply the cream on the insides of your mouth, anus, or genitals. Wash your hands again after you’ve finished your application. Apply the cream every 4 hours, 5 times a day. You will usually use the cream every day for 5 days, but if your cold sore or genital sores have not healed you can continue treatment for another 5 days.


Side Effects 

Like all medications, aciclovir can have side effects, although not everyone will experience them. If you experience any of the following side effects then you may be experiencing a severe allergic reaction and should stop use and seek immediate medical attention:

  • Hives, also known as nettle rash or urticaria, which causes red, raised, itchy, bumpy skin
  • Difficulty breathing or swallowing
  • Swelling of the eyes, lips, mouth, tongue, or throat

Serious side effects

Serious side effects of Aciclovir cream can include:

  • Symptoms of a severe allergic reaction, including swelling of the face, mouth, tongue or throat, difficulty breathing or swallowing, an itchy skin rash, and hives.
  • Harmful blood clots in a vein or artery.
  • An increased risk of Breast Cancer
  • Severe liver problems
  • Increased blood pressure
  • Increased risk of Fits

If you experience these or any other side effects you should speak to your doctor or pharmacist right away. For more information about reporting the side effects of medication, you should see the MHRA’s Yellow Card Scheme.



Do not use aciclovir cream if you are allergic to aciclovir, valaciclovir, or any of the other listed ingredients in this medication. For external use only, avoid contact with the eyes, inside of the mouth, inside of the genitals, and other sensitive areas. Let your prescriber know during your first consultation if you have any condition which means that your immune system is not working properly, as this may affect whether you can use this treatment or if you will need a different dose than usual.

Pregnancy and Breastfeeding

You should tell your prescriber during your consultation if you are pregnant or breastfeeding, as you may not be able to use aciclovir at this time. You should limit the medications you use as much as possible during pregnancy, including this treatment, but if your prescriber determines that your need for this medicine is greater than the potential effects it could have on your pregnancy, aciclovir may still be right for you. With that being said, you should not take any medication until you’re given the all-clear by a medical professional, as they will be able to make sure your treatments are right for both you and your baby.


Important information

This product is a medicine; make sure to speak to your doctor or Chemist4U pharmacist before taking this product if you have an underlying medical problem or are taking any other medicine or complementary therapy. If your symptoms get worse or continue after taking this product, contact us or your doctor. For medical services in your area, please refer to

If you are pregnant, trying to become pregnant, or breastfeeding, speak to your doctor or our pharmacist before taking this product. If you suffer from any allergies, ask your doctor or our pharmacist if this medicine is right for you.

Store all medicines out of sight and reach of children.

Please read the included leaflet carefully before using this product.

Please contact your GP if appropriate regarding this product.



Store in a cool, dry place which is below 25 degrees C. Do not use this product if the expiry date printed on the original packaging has passed. Keep out of sight and reach of children.

Frequently Asked Questions

Are cold sores and herpes the same thing?

Cold sores and herpes are very similar, both forming sores or blisters and causing itching, burning, or tingling in the affected area.

They’re so similar because they’re caused by the same virus, which is called herpes simplex.

The herpes virus doesn’t have a cure, but it’s harmless and if you catch it it will just live in one area of your skin, usually around your mouth or genitals, and make itself known every so often.

Herpes simplex is very contagious when you have sores or blisters, so you’ll have to be very careful not to pass it on to anyone else during a flare-up.

It’s passed on through skin-to-skin contact, such as kissing or during sex, so it’s vital that you take notice when you think you’re about to get herpes sores and take the necessary precautions to keep the virus from spreading to someone else.

What is a cold sore?

Cold sores are small blisters that usually appear on your lips, although they can appear anywhere on the face.

They are often grouped together and appear on or around your lips due to the herpes simplex virus.

Cold sores are caused by a virus that lives in your skin, flaring up every so often to form itchy, contagious blisters.

When this blister bursts, the cold sore will scab over, usually disappearing in a couple of weeks without leaving a scar.

They’re very contagious and can be spread by close contact like kissing or sharing cutlery.

When you have the virus you can get a cold sore at any time, although you may find that some things, like illnesses or your period, can cause flare-ups.

Cold sores are harmless, although they can feel itchy, burning, and irritating, and they’ll usually clear up on their own within 10 days.

However, if your cold sores are very large, painful, or keep coming back, you may benefit from a prescription treatment like aciclovir to help keep them under control.

What is herpes?

There are several different types of herpes virus, including herpes zoster (shingles) and varicella zoster (chickenpox) - but the most common and recognisable type is the herpes simplex virus, also known as HSV. There are two types of herpes simplex virus: 


This causes oral herpes, leading to cold sores and blisters around the mouth or face. HSV-1 can be contracted by interactions such as kissing, sharing a lip balm, or eating from the same utensils as someone who has HSV-1. 


This is contracted through sexual contact with someone who has HSV-2, causing genital herpes. Unlike HSV-1, which can be contracted from a person without any symptoms, HSV-2 usually spreads through direct contact with a herpes sore. 

There’s currently no cure for herpes simplex - once you’ve become infected, the virus remains in your body and sores may come and go throughout your life. Fortunately, sores can go away by themselves or with simple treatments like aciclovir.

Do I need a prescription for this medication?

You do need a prescription for this medication in the UK.

Our healthcare professionals can provide prescriptions if they think this treatment would be right for you and your condition.

When you click the button which reads “Start Consultation” at the top of this page, you’ll see a short questionnaire set up by our healthcare team which is designed to help them understand your medical needs.

Just like an in-person consultation with your GP, our doctors will assess your answers to their questions and write a prescription for the treatment they think will be best for you.

You’ll then be able to pay for your medication and we’ll send it out to you quickly and in discreet packaging.

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